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国际口腔科学研究

International Oral Science Research

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International Oral Science Research. 2025; 4: (1) ; 10.12208/j.iosr.20250003 .

Analysis of the effect of basic periodontal therapy combined with tinidazole capsules in the treatment of diabetic periodontitis
牙周基础治疗联合替硝唑胶囊治疗糖尿病性牙周炎的效果分析

作者： 明勇 *

巴中市巴州区第二人民医院 四川巴中

*通讯作者： 明勇,单位：巴中市巴州区第二人民医院 四川巴中；

引用本文: 明勇 牙周基础治疗联合替硝唑胶囊治疗糖尿病性牙周炎的效果分析[J]. 国际口腔科学研究, 2025; 4: (1) : 12-14.
Published: 2025/6/27 10:05:29

摘要

目的 分析牙周基础治疗联合替硝唑胶囊治疗糖尿病性牙周炎的效果。方法 本次选择80例患者，时间为2020年3月份至2024年3月份，参与的患者分成了两组，对照组与实验组，每组40例，对照组常规治疗；实验组在对照组基础上提供替硝唑胶囊口服，对比两组治疗前后牙龈指数（GI）、改良龈沟出血指数（BI）、牙周探诊深度（PD）、附着丧失（AL）、牙齿松动度及糖化血红蛋白（HbA1c）水平。结果 治疗后，实验组GI、BI、PD、AL及牙齿松动度改善均显著优于对照组（均p<0.05），但两组HbA1c水平无统计学差异（p>0.05）。结论 对糖尿病性牙周炎患者提供常规治疗的同时，添加替硝唑胶囊口服治疗，可以促进炎症的消退，提高患者的牙周附着水平，改善患者的牙周指标。

关键词： 牙周基础治疗；替硝唑胶囊；糖尿病性牙周炎

Abstract

Objective To analyze the efficacy of basic periodontal therapy combined with tinidazole capsules in the treatment of diabetic periodontitis.
Methods Eighty patients were enrolled between March 2020 and March 2024 and divided into two groups: a control group and an experimental group, with 40 patients in each group. The control group received conventional treatment; the experimental group received oral tinidazole capsules in addition to the control group's treatment. Gingival index (GI), modified sulcus bleeding index (BI), periodontal probing depth (PD), attachment loss (AL), tooth mobility, and glycated hemoglobin (HbA1c) levels were compared between the two groups before and after treatment.
Results After treatment, improvements in GI, BI, PD, AL, and tooth mobility were significantly greater in the experimental group than in the control group (all p < 0.05), but there was no statistical difference in HbA1c levels between the two groups (p > 0.05).
Conclusion   Adding oral tinidazole capsules to conventional treatment for patients with diabetic periodontitis can promote the resolution of inflammation, improve periodontal attachment, and improve periodontal indicators.

Key words： Primary periodontal therapy; Tinidazole capsules; Diabetic periodontitis

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