For indications in combination with calcium hydroxide on root canal treatment of chronic apicalperiarthritis of clinical research
替硝唑联合氢氧化钙在根管治疗慢性根尖周炎中的临床作用研究

摘要

目的 分析替硝唑联合氢氧化钙在根管治疗慢性根尖周炎中的临床作用研究。方法 此次实验对象为慢性根尖周炎患者，入院时间均在2019年10月至2021年10月，入选患者共100例，利用随机抽取双色球法进行分组，分为对照组（氢氧化钙，n=50）与实验组（氢氧化钙+替硝唑，n=50）。对比两组的牙周指数、炎症因子、疗效及不良反应。结果 在菌斑指数、牙龈指数及牙周探诊深度上，实验组低于对照组（P＜0.05）。在白细胞介素-1β（IL-1β）、肿瘤坏死因子（TNF-α）上，实验组低于对照组（P＜0.05）。在临床疗效上，实验组高于对照组（P＜0.05）。在不良反应发生率上，实验组低于对照组（P＜0.05）。结论 针对慢性根尖周炎患者，实施替硝唑+氢氧化钙治疗的效果显著，有利于改善牙周指数，临床可进一步推广应用。

Abstract

Objective to analyze indications with calcium hydroxide on root canal therapy for chronic periarthritis of root tips in clinical research.
Methods the subjects for the patients with chronic periarthritis of root, admitted to hospital in time for 2019.10 months and 2021.10 months, for a total of 100 cases of patients, using random grouping method of the double chromosphere, divided into the control group (calcium hydroxide, n = 50) and the experimental group (indications for calcium hydroxide, n = 50).Comparison of two groups of periodontal index, inflammation factors, efficacy and adverse reactions.
Results of the plaque index, gingival index and periodontal probing depth, the experimental group is lower than the control group (P < 0.05). In beta interleukins - 1 (IL - 1 beta), tumor necrosis factor (TNF alpha), the experimental group is lower than the control group (P < 0.05). On the clinical curative effect, the experimental group was higher than control group (P < 0.05). On the incidence of adverse reactions, the experimental group is lower than the control group (P < 0.05).
Conclusion   for patients with chronic periarthritis of root, the implementation for indications of calcium hydroxide treatment effect is remarkable, is conducive to better periodontal index, clinical can further popularization and application.