Yishen Guwei Decoction combined with acupoint catgut embedding in the treatment of chronic urticaria onTCM syndrome scores and improvement of serum total IgE level
益肾固卫汤配合穴位埋线治疗慢性荨麻疹对中医证候积分及血清总IgE水平的改善

摘要

目的 分析益肾固卫汤配合穴位埋线治疗慢性荨麻疹对中医证候积分及血清总IgE水平的改善。方法 入组本院2021年1月-2021年12月收治的慢性荨麻疹患者共70例，随机分组，对照组的患者用药处方是盐酸西替利嗪、依巴斯汀，观察组则在对照组的基础上增加益肾固卫汤配合穴位埋线治疗。比较两组治疗前后患者中医证候积分及血清总IgE水平、生活质量评分、慢性荨麻疹治疗总有效率、不良反应。结果 治疗前二组病患中医证候积分及血清总IgE水平、生活质量评分比较，P＞0.05，治疗后，两组患者中医证候积分及血清总IgE水平均显著降低，生活质量评分均显著提高，P＜0.05。而其中，治疗后观察组中医证候积分及血清总IgE水平显著低于对照组，生活质量评分显著高于对照组，P＜0.05。观察组治疗总有效率高于对照组，P＜0.05。两组不良反应对比没有明显差异，均1例恶心，发生率2.86%，χ2=0.00,P＞0.05。结论 盐酸西替利嗪、依巴斯汀与益肾固卫汤配合穴位埋线治疗对于慢性荨麻疹的效果确切，可改善患者症状和生活质量，值得推广。

Abstract

Objective To analyze the improvement of TCM syndrome score and serum total IgE level in the treatment of chronic urticaria with Yishen Guwei Decoction and acupoint catgut embedding.
Methods A total of 70 patients with chronic urticaria who were treated in our hospital from January 2021 to December 2021 were enrolled and randomly divided into groups. The patients in the control group were prescribed cetirizine hydrochloride and ebastine, while those in the observation group were in the control group. On the basis of the group, Yishen Guwei decoction combined with acupoint catgut embedding therapy was added. The TCM syndrome score, serum total IgE level, quality of life score, total effective rate and adverse reactions of chronic urticaria were compared between the two groups before and after treatment.
Results Before treatment, the TCM syndrome scores, serum total IgE levels, and quality of life scores of the two groups of patients were compared, P>0.05. After treatment, the TCM syndrome scores and serum total IgE levels of the two groups of patients were significantly reduced, and the quality of life scores were significantly lower. increase, P<0.05. Among them, after treatment, the TCM syndrome scores and serum total IgE level in the observation group were significantly lower than those in the control group, and the quality of life score was significantly higher than that in the control group, P<0.05. The total effective rate of the observation group was higher than that of the control group, P<0.05. There was no significant difference in adverse reactions between the two groups. There was 1 case of nausea, and the incidence was 2.86%, χ2=0.00, P>0.05.
Conclusion   Cetirizine hydrochloride, ebastine and Yishen Guwei decoction combined with acupoint catgut embedding therapy have definite effect on chronic urticaria, and can improve the symptoms and quality of life of patients, which is worthy of promotion.