Significance of serum C-reactive protein and WBC levels in diagnosis of fever in children
血清C－反应蛋白及WBC水平检验诊断小儿发热的意义

摘要

目的 探讨血清C－反应蛋白及WBC水平检验诊断小儿发热的意义。方法 本次研究将采用抽样调查和分组研究的方法，首先通过抽样调查法选取参与研究的对象，从2020年1月到2021年1月期间就医的发热患儿中抽选120例，将所有患儿按照出院诊断结果分为细菌感染组（n=40例）、病毒感染组（n=40例）和风湿性疾病组（n=40例），再选取同期的健康儿童40例设置为对照组，对四组儿童进行血清C－反应蛋白及WBC水平检验，对比四组儿童的检测结果。结果 血清C－反应蛋白水平：风湿性疾病组＞细菌感染组＞病毒感染组＞对照组；WBC水平：细菌感染组＞风湿性疾病组＞对照组＞病毒感染组，数据对比均有统计学意义（P＜0.05）；细菌感染组阳性检出率最高，其次为风湿性疾病组和病毒感染组，对照组阳性检出率最低。结论 血清C－反应蛋白及WBC水平检验能够为小儿发热的临床诊断提供可靠的数据参考。

Abstract

Objective To explore the significance of serum C-reactive protein and WBC levels in the diagnosis of fever in children.
Methods This study will adopt the methods of sampling survey and group study. Firstly, the subjects participating in the study will be selected through sampling survey. 120 febrile children will be selected from the period from January 2020 to January 2021. All children will be divided into bacterial infection group (n=40 cases), virus infection group (n=40 cases) and rheumatic disease group (n=40 cases) according to the discharge diagnosis results, and then 40 healthy children in the same period will be selected as the control group, The levels of serum C-reactive protein and WBC in four groups of children were tested, and the test results of four groups of children were compared.
Results the level of serum C-reactive protein was: rheumatic disease group > bacterial infection group > viral infection group > control group; WBC level: bacterial infection group > rheumatic disease group > control group > virus infection group, the data were statistically significant P; The positive rate of bacterial infection group was the highest, followed by rheumatic disease group and virus infection group, and the positive rate of control group was the lowest.
Conclusion   the levels of serum C-reactive protein and WBC can provide reliable data reference for the clinical diagnosis of fever in children.