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国际医学与数据杂志

International Journal of Medicine and Data

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International Journal of Medicine and Data. 2022; 6: (2) ; 10.12208/ j.ijmd.20220088 .

Effect of metoprolol in the treatment of chronic heart failure
美托洛尔治疗慢性心力衰竭的效果

作者: 郭霞 *

河北省张家口市张北县花园街社区卫生健康服务中心 河北张家口

*通讯作者: 郭霞,单位:河北省张家口市张北县花园街社区卫生健康服务中心 河北张家口;

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引用本文: 郭霞 美托洛尔治疗慢性心力衰竭的效果[J]. 国际医学与数据杂志, 2022; 6: (2) : 173-175.
Published: 2022/7/25 11:53:12

摘要

目的 研究美托洛尔治疗慢性心力衰竭的效果。方法 选择2020年01月-2021年12月到本院治疗慢性心力衰竭的患者共100例,按照治疗方式的不同,分为实验组和对照组,分析治疗效果。结果 治疗前,两组患者各项指标对比,P>0.05;治疗后,实验组患者LVEF指标、LVED指标以及6min步行距离均优于对照组,P<0.05,其中实验组患者LVEF指标为48.12±0.35/%、LVEDD指标为35.86±1.12/mm、6min步行距离568.34±44.22(m);实验组不良反应总发生率3(6.00%)低于对照组10(20.00%),P<0.05,其中实验组低血压发生率1(2.00%)、血管性水肿发生率1(2.00%)、干咳发生率1(2.00%);实验组患者治疗后不良事件发生概率3(6.00%)低于对照组11(22.00%),其中实验组心力衰竭复发率1(2.00%)、恶性心律失常率1(2.00%)、心源性休克率1(2.00%)、心源性死亡率0(0.00%)、再入院率0(0.00%),P<0.05。结论 慢性心力衰竭疾病的发病概率比较高,而且致死的概率也比较高。美托洛尔药物可显著将慢性心力衰竭患者的心脏功能加以改善,降低此疾病病死概率,疗效确切,可运用。

关键词: 美托洛尔;慢性心力衰竭;LVEF指标;LVED指标;不良反应

Abstract

Objective To study the effect of metoprolol on chronic heart failure.
Methods 100 patients with chronic heart failure treated in our hospital from January 2020 to December 2021 were divided into experimental group and control group according to different treatment methods, and the treatment effect was analyzed.
Results before treatment, the indexes of the two groups were compared (P > 0.05); After treatment, the LVEF index, lved index and 6-min walking distance in the experimental group were better than those in the control group (P < 0.05). The LVEF index, LVEDd index and 6-min walking distance in the experimental group were 48.12 ± 0.35 /%, 35.86 ± 1.12/mm and 568.34 ± 44.22 (m); The total incidence of adverse reactions in the experimental group was 3 (6.00%) lower than that in the control group 10 (20.00%), P < 0.05. The incidence of hypotension in the experimental group was 1 (2.00%), the incidence of angioedema was 1 (2.00%), and the incidence of dry cough was 1 (2.00%); The incidence rate of adverse events in the experimental group was 3 (6.00%) lower than that in the control group 11 (22.00%), among which the recurrence rate of heart failure in the experimental group was 1 (2.00%), the rate of malignant arrhythmia was 1 (2.00%), the rate of cardiogenic shock was 1 (2.00%), the rate of cardiogenic mortality was 0 (0.00%), and the rate of readmission was 0 (0.00%), P < 0.05.
Conclusion   the incidence of chronic heart failure is relatively high, and the probability of death is also relatively high. Metoprolol can significantly improve the cardiac function of patients with chronic heart failure and reduce the mortality of this disease. It has definite curative effect and can be used.

Key words: Metoprolol; Chronic heart failure; LVEF index; Lved index; Adverse reaction

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