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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2022; 6: (5) ; 10.12208/j.ijcr.20220215 .

Effect of intensive nursing intervention on intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
强化护理干预对异基因造血干细胞移植术后并发肠道移植物抗宿主病的疗效

作者: 蒋侠 *, 耿婷婷

中山大学附属第三医院岭南医院 广东广州

*通讯作者: 蒋侠,单位:中山大学附属第三医院岭南医院 广东广州;

引用本文: 蒋侠, 耿婷婷 强化护理干预对异基因造血干细胞移植术后并发肠道移植物抗宿主病的疗效[J]. 国际临床研究杂志, 2022; 6: (5) : 75-77.
Published: 2022/7/16 17:30:50

摘要

目的 探析强化护理干预对异基因造血干细胞移植术后并发肠道移植物抗宿主病的疗效。方法 择选我院2019.1-2022.1期间临床收治异基因造血干细胞移植术治疗者共计70名,术后体查均存并发肠道移植物抗宿主病。建立信封法平均分组两组即为常规组、实验组,每组35名。予以常规组常规护理干预,予以实验组强化护理干预。对比两组的护理满意度、病程与住院时间。结果 干预后实验组护理满意度高于常规组,P<0.05。实验组病程与住院时间低于常规组,P<0.05。结论 对异基因造血干细胞移植术后并发肠道移植物抗宿主病人建立强化护理干预方案可缩短其康复时间,提高服务质量评价,建议推广应用。

关键词: 异基因造血干细胞移植;肠道移植物抗宿主病;强化护理;效果

Abstract

Objective: To explore the effect of intensive nursing intervention on intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Methods: a total of 70 patients treated with allogeneic hematopoietic stem cell transplantation in our hospital from January 2019 to February 2022 were selected. Postoperative physical examination showed that they were complicated with intestinal graft-versus-host disease. The envelope method was established and divided into two groups: routine group and experimental group, with 35 people in each group. Routine nursing intervention was given to the routine group and intensive nursing intervention was given to the experimental group. The nursing satisfaction, course of disease and length of hospital stay, and the scores of adverse emotions before and after nursing were compared between the two groups.
Results: before the intervention, the scores of bad emotions in the two groups were compared (P > 0.05). After the intervention, the nursing satisfaction of the experimental group was higher than that of the routine group (P < 0.05). The course of disease, length of hospital stay and adverse emotion score in the experimental group were lower than those in the routine group (P < 0.05).
Conclusion  : the establishment of intensive nursing intervention program for patients with intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation can shorten their rehabilitation leave and improve the evaluation of service quality. It is suggested to popularize it.

Key words: Allogeneic Hematopoietic Stem Cell Transplantation; Intestinal Graft Versus Host Disease; Intensive Nursing; Effect

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