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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2022; 6: (5) ; 10.12208/j.ijcr.20220210 .

Clinical characteristics of minocycline hydrochloride in the treatment of dermatosis and venereal diseases
盐酸米诺环素在皮肤病性病治疗中的临床特点研究

作者: 邵丹 *

开远市人民医院 云南开远

*通讯作者: 邵丹,单位:开远市人民医院 云南开远;

引用本文: 邵丹 盐酸米诺环素在皮肤病性病治疗中的临床特点研究[J]. 国际临床研究杂志, 2022; 6: (5) : 60-62.
Published: 2022/7/16 17:19:01

摘要

目的 为加快皮肤病性病患者康复,改善患者预后效果,针对盐酸米诺环素在皮肤病性病患者治疗中的临床特点及应用价值做深入研究,为临床治疗提供有效参考依据。方法 回顾性分析2022年1月-2022年3月期间在本院接受治疗的皮肤病性病患者,共计30例,根据患者疾病类型分为三组(每组各10例)。观察1组(非淋球菌性尿道炎),观察2组(痤疮类),观察3组(皮肤感染类),根据病情实施不同剂量盐酸米诺环素,对比治疗总有效率。结果 经过两周的治疗,治疗总有效率观察1组80%、观察2组70%、观察3组100%,观察3组最高,组间数据P<0.05,差异具有统计学意义。结论 分析表明,采用盐酸米诺环素治疗皮肤病性病,可起到明显的临床治疗效果,同时加快患者康复时间,改善患者预后质量,尤其对皮肤感染类患者治疗效果最为显著,可用性较高,对此建议大力推广此项治疗方案。

关键词: 盐酸米诺环素;皮肤病性病;临床特点;治疗效果

Abstract

Objective: in order to speed up the rehabilitation of patients with skin diseases and sexually transmitted diseases and improve the prognosis of patients, we made an in-depth study on the clinical characteristics and application value of minocycline hydrochloride in the treatment of patients with skin diseases and sexually transmitted diseases, so as to provide effective reference basis for clinical treatment.
Methods: a total of 30 patients with skin diseases and sexually transmitted diseases treated in our hospital from January 2022 to March 2022 were analyzed retrospectively. They were divided into three groups (10 cases in each group) according to the type of disease. Observation group 1 (non gonococcal urethritis), observation group 2 (acne) and observation group 3 (skin infection). Different doses of minocycline hydrochloride were implemented according to the condition, and the total effective rate was compared.
Results: after two weeks of treatment, the total effective rate of observation group 1 was 80%, observation group 2 was 70%, and observation group 3 was 100%. The highest rate was observed in the three groups (P < 0.05).
Conclusion  : the analysis shows that minocycline hydrochloride can play an obvious clinical therapeutic effect in the treatment of dermatological and venereal diseases, accelerate the recovery time of patients and improve the prognosis of patients, especially for patients with skin infection. It has the most significant therapeutic effect and high availability. Therefore, it is suggested to vigorously promote this treatment scheme.

Key words: Minocycline Hydrochloride; Dermatosis And Venereal Diseases; Clinical Features; Treatment Effect

参考文献 References

[1] 冯晓然,李萌萌,黎静宜,等.盐酸米诺环素联合外用糖皮质激素治疗疱疹样天疱疮一例[J].中国麻风皮肤病杂志, 2021, 37(7):451-453.

[2] 陈春丽,常慧杰,李燕娜.盐酸米诺环素胶囊联合果酸治疗痤疮的疗效观察[J]. 皮肤病与性病,2021,43(4): 589-590.

[3] 邹积阳.盐酸米诺环素在皮肤性病治疗中的临床特点分析[J].名医,2019(1):271.

[4] 田雅瑞,张道军,朱堂友,等.盐酸米诺环素胶囊口服配合多功能激光光电平台治疗玫瑰痤疮疗效观察[J].皮肤病与性病,2019,41(6):850-852.

[5] 李小英.外涂20%超分子水杨酸及口服盐酸米诺环素联合红蓝光治疗中重度痤疮51例[J].安徽医药,2021,25(2): 366-369. 

[6] 刘洁,孙静,郝丹,等.盐酸米诺环素治疗游泳池肉芽肿报告1例[J].中国中西医结合皮肤性病学杂志,2019, 18(1):78-79. 

[7] 蔡琳,侯冰,王健彬,等.丹参酮联合米诺环素治疗寻常型痤疮的临床疗效及对血清炎症因子的影响[J].皮肤病与性病,2019,41(6):826-827. 

[8] 王刚.点阵铒激光联合盐酸米诺环素和夫西地酸乳膏治疗萎缩性痤疮瘢痕的临床研究[J].中国激光医学杂志,2020,29(6):342-347.

[9] 乔国安,张晓忠,杨晶雪.盐酸米诺环素在皮肤病性病治疗中的临床特点研究[J].航空航天医学杂志,2021, 32(12): 1424-1425. 

[10] 孙铮,郑玲玲.龙珠软膏联合盐酸米诺环素胶囊治疗轻中度寻常型痤疮的疗效评价[J].中国麻风皮肤病杂志,2021,37(7):448-450.

[11] 王红燕,刘娜,肖洁平,等.盐酸米诺环素胶囊联合激光治疗痤疮患者的临床研究[J].中国临床药理学杂志,2021, 37(18): 2413-2415.

[12] 燕红霞.盐酸米诺环素胶囊在皮肤病治疗中的临床特点[J].中国继续医学教育,2019,11(7):115-117.