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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2022; 6: (4) ; 10.12208/j.ijcr.20220187 .

Efficacy of daplamide combined with amlodipine in the treatment of hypertension complicated with coronary heart disease
吲达帕胺合氨氯地平治疗高血压合并冠心病的疗效

作者: 穆勤凯 *

清镇市新店镇中心卫生院 贵州清镇

*通讯作者: 穆勤凯,单位:清镇市新店镇中心卫生院 贵州清镇;

引用本文: 穆勤凯 吲达帕胺合氨氯地平治疗高血压合并冠心病的疗效[J]. 国际临床研究杂志, 2022; 6: (4) : 158-160.
Published: 2022/6/30 15:21:40

摘要

目的 研究高血压合并冠心病采取吲达帕胺、氨氯地平一起治疗产生的作用。方法 实验对象:58例高血压合并冠心病患者。实验时间:2020年1月到2021年1月。实验分组方式:随机数表方式。实验分组类别:对照组实施氨氯地平单独治疗,为29例;观察组实施吲达帕胺、氨氯地平一起治疗,为29例。结果 观察组治疗后总有效率显著较高,观察组治疗后收缩压、舒张压明显降低,差异具有统计学意义,(P<0.05)。观察组和对照组不良反应发生率均较低,无明显差异,(P>0.05)。结论 吲达帕胺、氨氯地平一起应用于此次病证中治疗能够稳定血压,治疗效果较明显,安全性较高,值得临床重视。

关键词: 吲达帕胺;氨氯地平;高血压;冠心病;疗效

Abstract

Objective To study the effect of indapamide and amlodipine on hypertension complicated with coronary heart disease.
Methods: Subjects: 58 patients with hypertension complicated with coronary heart disease. Experiment time: January 2020 to January 2021. Experimental grouping: random number table. Experimental grouping category: 29 cases in the control group were treated with amlodipine alone; In the observation group, 29 cases were treated with indapamide and amlodipine.
Results: the total effective rate of the observation group was significantly higher after treatment, and the systolic and diastolic blood pressure of the observation group decreased significantly after treatment (P < 0.05). The incidence of adverse reactions in the observation group and the control group was low, and there was no significant difference (P > 0.05).
Conclusion  : indapamide and amlodipine can stabilize blood pressure in the treatment of this syndrome, with obvious therapeutic effect and high safety, which is worthy of clinical attention.

Key words: Indapamide; Amlodipine; Hypertension; Coronary Heart Disease; Curative Effect

参考文献 References

[1] 范海芳.吲达帕胺联合氨氯地平治疗高血压合并冠心病的效果[J].中国实用医药,2021,16(14):150-152.

[2] 张玉洁.吲达帕胺联合氨氯地平对高血压合并冠心病患者心功能与生活质量的影响分析[J].心血管病防治知识,2021,11(08):28-30.

[3] 季丽丽,王高频.吲达帕胺、氨氯地平联合治疗高血压合并冠心病的疗效分析[J].中国社区医师,2020,36(36): 18-19.

[4] 纪斌,张莉巩,新成.吲达帕胺联合氨氯地平治疗高血压合并冠心病临床疗效观察[J].中国社区医师,2020,36(31): 76-77.

[5] 张玉新.吲达帕胺联合氨氯地平治疗高血压合并冠心病的疗效[J].中西医结合心血管病电子杂志,2020,8(30): 64-65.

[6] 张敏,康丹丹,赵志刚.吲达帕胺联合苯磺酸左旋氨氯地平治疗高血压合并冠心病的效果对血管内皮功能及IMT的影响[J].哈尔滨医药,2020,40(04):301-303.

[7] 郭峥,李晓红.吲达帕胺、氨氯地平联合治疗高血压合并冠心病的疗效观察[J].中国医药指南,2020,18(18):76-77.