The value of intra-amniotic injection of rivanol combined with oral mifepristonein mid-trimester pregnancy induction
利凡诺羊膜腔内注射配合口服米非司酮中期妊娠引产中的价值

摘要

目的 分析探究中期妊娠引产中采取利凡诺羊膜腔内注射配合口服米非司酮的效果。方法 58例研究对象为本院于2020年2月-2021年2月期间收治的中期妊娠引产孕妇。将上述研究对象采取信封抽签法进行分组，其中一种设定为对照组，此组所采取的治疗方法为利凡诺羊膜腔内注射，另一组设定为实验组，本组采取的治疗方法为利凡诺羊膜腔内注射配合口服米非司酮，每组皆有29例孕妇。为了验证利凡诺羊膜腔内注射配合口服米非司酮在中期妊娠引产中的效果，本次研究以引产情况、产后出血量、产程时间、引产成功率、清宫率以及满意度情况予以评价。结果 实验组的引产情况和对照组进行了比较，结果可见实验组较优（P＜0.05）。实验组的产后2小时出血量和对照组进行了对比，结果可见实验组较低（P＜0.05）。实验组产程时间和对照组进行了比较，结果可见实验组较短（P＜0.05）。实验组的引产成功率、清宫率和对照组进行比较，结果可见实验组较高（P＜0.05）。实验组的满意度和对照组进行了对比，结果可见实验组较高P＜0.05）。结论 在中期妊娠引产中施行利凡诺羊膜腔内注射配合口服米非司酮治疗，可显著改善孕妇引产情况，同时能够降低出血量，提升引产成功率以及清宫率，进而对孕妇及家属的满意度予以提高。由此看来，此种联合方法在中期妊娠引产中具有重要的意义。

Abstract

Objective To analyze the effect of intra-amniotic injection of rivanol combined with oral mifepristone in the induction of labor in the second trimester.
Methods Fifty-eight cases of pregnant women who were admitted to our hospital from February 2020 to February 2021 for induced labor were included in the study. The above research subjects were divided into groups by the envelope drawing method, one of which was set as the control group, the treatment method adopted in this group was intra-amniotic injection of Rivanol, and the other group was set as the experimental group.
Methods The intra-amniotic injection of Rivanol and oral administration of mifepristone were performed. There were 29 pregnant women in each group. In order to verify the effect of intra-amniotic injection of rivanol combined with oral mifepristone in the induction of labor in the second trimester, this study evaluated labor induction, postpartum hemorrhage, labor duration, success rate of labor induction, uterine clearance rate, and satisfaction.
Results The induction of labor in the experimental group was compared with that in the control group, and the results showed that the experimental group was better (P<0.05). The postpartum hemorrhage volume of the experimental group was compared with that of the control group, and the results showed that the experimental group was lower (P<0.05). The labor time of the experimental group was compared with that of the control group, and the results showed that the experimental group was shorter (P<0.05). Compared with the control group, the success rate of labor induction and the rate of clearing the uterus in the experimental group were higher than those in the control group (P<0.05). The satisfaction of the experimental group was compared with that of the control group, and the results showed that the experimental group was higher (P<0.05).
Conclusion   Rivanol intra-amniotic injection combined with oral mifepristone therapy in mid-trimester pregnancy induction can significantly improve the induction of labor in pregnant women, reduce the amount of blood loss, increase the success rate of labor induction and the rate of uterine clearance, and thus satisfy pregnant women and their families. degree be improved. From this point of view, this combined method is of great significance in the induction of labor in the second trimester.