Clinical effect of anticoagulation therapy in patients with atrial fibrillation in the Department of Cardiology
心内科房颤患者抗凝治疗的临床效果研究

摘要

目的 心内科房颤患者抗凝治疗的临床效果研究。方法 自2021年度1月至2021年12月选择84例因房颤而就诊于我科室的病人进行调研，按照治疗举措将其归纳为2个小组，每组均纳入42例病人。按照治疗手段，将其命名为常规组与调研组。常规组在本次调研中所采用的治疗方案为阿司匹林单纯治疗，调研组在本次调研中所采用的治疗方案为法华林治疗。总结与探究2种治疗方案实施效果。结果 经过治疗常规组与调研组血小板分布宽度、血小板水平、凝血酶原时间、D-二聚体均有所改善，常规组与治疗前相比血小板分布宽度降低、血小板水平降低、凝血酶原时间提高、D-二聚体降低，与治疗前相比，组间有一定差异，（P<0.05）；调研组与治疗前相比血小板分布宽度降低、血小板水平降低、凝血酶原时间提高、D-二聚体降低，与治疗前相比，组间有一定差异，（P<0.05）。虽然经过治疗，常规组与调研组指标水平改善，是常规组和调研组在比较，血小板水平高于调研组、凝血酶原时间低于调研组、D-二聚体高于调研组，两组对照，差异明显，（P<0.05）。结论 房颤治疗中法华林抗凝治疗效果优异，此方案值得临床应用与普及。

Abstract

Objective: To study the clinical effect of anticoagulation in patients with atrial fibrillation in the department of cardiology.
Methods From January 2021 to December 2021, 84 patients who were admitted to our department due to atrial fibrillation were selected for investigation. They were divided into 2 groups according to the treatment measures, and each group included 42 patients. According to the treatment methods, they were named as routine group and investigation group. The treatment plan adopted by the routine group in this investigation was aspirin alone, and the treatment plan adopted by the investigation group in this investigation was warfarin treatment. Summarize and explore the implementation effect of the two treatment programs.
Results After treatment, the platelet distribution width, platelet level, prothrombin time, and D-dimer in the routine group and the investigation group were improved. Compared with before treatment, the routine group decreased platelet distribution width, platelet level, and prothrombin time. Compared with before treatment, there was a certain difference between the groups (P<0.05). Compared with before treatment, the investigation group decreased platelet distribution width, decreased platelet level, increased prothrombin time, and increased D-dimer. -Dimer decreased, compared with before treatment, there was a certain difference between groups (P<0.05). Although after treatment, the index levels of the routine group and the investigation group improved, which is the comparison between the routine group and the investigation group. The level of platelets was higher than that of the investigation group, the prothrombin time was lower than that of the investigation group, and the D-dimer was higher than that of the investigation group. , the difference was significant, (P<0.05).
Conclusion   Warlin anticoagulation has an excellent effect in the treatment of atrial fibrillation, and this program is worthy of clinical application and popularization.