Analysis of the application value of intensive insulin pump therapy in the treatment of newly-treated type 2 diabetes
胰岛素泵强化治疗在初治2型糖尿病治疗中的应用价值分析

摘要

目的 分析在初治2型糖尿病患者中应用胰岛素泵强化治疗的价值。方法 于本院2019年5月-2020年5月治疗的初治2型糖尿病患者中遴选106例实施全面分析，全部患者诊疗资料均完整保存，研究分组方式为方便抽样法，将53例患者纳入参照组，予以胰岛素皮下注射强化治疗，剩余53例患者纳入研究组，予以胰岛素泵强化治疗，比较各组临床疗效、血糖水平、β细胞功能、治疗情况。结果 研究组临床总有效率为94.34%，明显较参照组（81.13%）高，P＜0.05；研究组治疗后的HbAIC、FPG、2hPG均显著较参照组低，P＜0.05；研究组治疗后的HOMA-IR水平显著较参照组低，HOMA-β水平显著较参照组高，P＜0.05；研究组低血糖发生率为1.89%，明显较参照组低，P＜0.05；研究组血糖达标时间明显较参照组早，胰岛素日使用量明显较参照组少，P＜0.05. 结论 予以初治2型糖尿病患者胰岛素泵强化治疗具有确切疗效，可显著改善血糖水平与β细胞功能，同时还可减少胰岛素日使用量，预防低血糖事件，临床应用价值理想。

Abstract

Objective: To analyze the value of intensive insulin pump therapy in newly treated patients with type 2 diabetes.
Methods: 106 cases of newly-treated type 2 diabetes patients treated in our hospital from May 2019 to May 2020 were selected for a comprehensive analysis. The diagnosis and treatment data of all patients were completely preserved. The study grouping method was convenient sampling method, and 53 patients were selected. Included in the reference group and received intensive subcutaneous injection of insulin. The remaining 53 patients were included in the study group and received intensive insulin pump treatment. The clinical efficacy, blood sugar level, β-cell function, and treatment status of each group were compared.
Results: The total clinical effective rate of the study group was 94.34%, which was significantly higher than that of the reference group (81.13%), P＜0.05; the HbAIC, FPG and 2hPG of the study group after treatment were significantly lower than those of the reference group, P＜0.05; treatment in the study group After HOMA-IR level was significantly lower than that of the reference group, HOMA-β level was significantly higher than that of the reference group, P<0.05; the incidence of hypoglycemia in the study group was 1.89%, which was significantly lower than that of the reference group, P<0.05; the blood glucose of the study group reached the standard The time was significantly earlier than that of the reference group, and the daily insulin consumption was significantly less than that of the reference group, P<0.05.
Conclusion  : Intensive insulin pump therapy for newly-treated patients with type 2 diabetes has a definite effect, which can significantly improve blood glucose levels and β-cell function, and also It can reduce the daily consumption of insulin, prevent hypoglycemia events, and has ideal clinical application value.