Clinical Observation of Different Methods to Prevent Phlebitis Caused by Acyclovir
不同方法预防阿昔洛韦药物所致静脉炎的临床疗效观察

摘要

目的：探讨不同方式预防阿昔洛韦所致静脉炎的临床效果。方法：选取我院接受阿昔洛韦静滴治疗的100例住院患者为研究对象，按随机原则将其分为三组：硫酸镁组(n=30)、水胶体组(n=30)及中长导管组(n=40)。硫酸镁组给予50％硫酸镁外敷预防静脉炎，水胶体组采取水胶体敷料外敷预防静脉炎，中长导管组置入中长导管预防静脉炎，评价不同方案对阿昔洛韦所致静脉炎的预防效果。结果：中长导管组静脉炎发生率较硫酸镁组及水胶体组均低，差异有统计学意义(P＜0.05)。结论：应用中长导管对需采取阿昔洛韦静滴治疗的患者进行输液可有效预防静脉炎发生，效果优于水胶体及硫酸镁。

Abstract

Objective:To explore the clinical effect of different ways to prevent phlebitis caused by acyclovir.
Methods:100 hospitalized patients who received acyclovir intravenous drip in our hospital were selected as the research objects and randomly divided into three groups:magnesium sulfate group(n=30),hydrocolloid group(n=30) and medium and long catheter group(n=40).The magnesium sulfate group was given 50% magnesium sulfate to prevent phlebitis,the hydrocolloid group was given hydrocolloid dressing to prevent phlebitis,and the medium and long catheter group was given medium and long catheter to prevent phlebitis.
Results:The incidence of phlebitis in the middle and long catheter group was lower than that in the magnesium sulfate group and hydrocolloid group,and the difference was statistically significant(P<0.05).
Conclusion  :The application of medium and long catheter in patients who need to take acyclovir intravenous infusion can effectively prevent phlebitis,and the effect is better than that of hydrocolloid and magnesium sulfate.