Nursing of patients with malignant tumors of oral and maxillofacial region before induction chemotherapy
口腔颌面部恶性肿瘤患者术前诱导化疗的护理

摘要

目的 探究口腔颌面部恶性肿瘤患者术前诱导化疗的护理措施。方法 本次实验中，主要探讨术前诱导化疗的护理措施，共选取了60例患者作为本次实验的研究对象，存在鳞癌、腺性上皮癌、基底细胞癌等，均符合入组标准。入组后采取数字法将患者分配为对照组和观察组，其中对照组需使用常规护理，观察组需在以上基础上使用综合护理，并在护理后对比不同护理方法在术前诱导化疗的应用效果，调查患者的不良反应发生率及QLQ-52评分。结果 通过分析来看，使用综合护理的观察组，在护理过程中出现1例胃肠反应，不良反应发生率3.32%；反观使用常规护理的对照组，护理过程中出现1例肾功能异常，2例胃肠反应，在1例骨髓抑制以及1例静脉炎，不良反应发生率16.66%，观察组不良反应发生率显著低于对照组，存在统计学意义，（P＜0.05）。其次，观察组患者的QLQ-52评分在术前诱导前与对照组间无较大差异，（P＜0.05），在术前诱导护理1周后、3周后，观察组QLQ-52评分有明显改善，较之对照组更优，（P＜0.05）。结论 对口腔颌面部恶性肿瘤患者在术前实施诱导化疗护理，对后续疗效的提升有积极意义，应用价值较高。

Abstract

Objective: To explore the nursing measures of preoperative induction chemotherapy for patients with malignant tumors of oral and maxillofacial region.
Methods: In this experiment, we mainly discussed the nursing measures of preoperative induction chemotherapy. A total of 60 patients were selected as the research objects of this experiment. There were squamous cell carcinoma, adenoepithelial carcinoma, and basal cell carcinoma, all of which met the inclusion criteria. . After enrollment, the patients were divided into a control group and an observation group using a digital method. The control group needed routine care, and the observation group needed comprehensive care on the basis of the above, and compared the different nursing methods in preoperative induction chemotherapy after care. Effect, to investigate the incidence of adverse reactions and QLQ-52 score of patients.
Results: According to the analysis, in the observation group using comprehensive nursing, 1 case of gastrointestinal reaction occurred during the nursing process, and the incidence of adverse reactions was 3.32%; in contrast, the control group using conventional nursing showed 1 case of abnormal renal function during the nursing process. In 2 cases of gastrointestinal reactions, in 1 case of bone marrow suppression and 1 case of phlebitis, the incidence of adverse reactions was 16.66%. The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P<0.05). Secondly, the QLQ-52 score of the observation group had no significant difference between the preoperative induction and the control group (P<0.05). After 1 week and 3 weeks of preoperative induction nursing, the QLQ-52 score of the observation group had Significantly improved, better than the control group (P<0.05).
Conclusion  : Carrying out induction chemotherapy nursing on patients with oral and maxillofacial malignant tumors before surgery has a positive significance for the subsequent improvement of efficacy and has high application value.