objective The research study the correlation between the cognition of Coronavirus disease 2019 (COVID-19) and the mental status about adult students in china, so as to provide reference for relevant institutions to take relevant health intervention measures. Methods in the period of the new coronavirus outbreak, the students who had delayed back to school due to the influence of the epidemic and were investigated by sending questionnaires online. Results students COVID - 19 knowledge questionnaire scores (74.82-4.76), higher levels, DASS - 21 emotional self rating scale total score (20.23±16.07) points, students prevention knowledge of COVID-19 and DASS - 21 pressure dimensions have significant (P < 0.05)..Conclusion s under the background of the rising number of cases of the new champions league pneumonia, students pay more attention to the COVID-9 and have a deeper understanding of the knowledge of the prevention of COVID-9,more in-depth knowledge of the new champions league pneumonia, negative emotions is small, the current situation of epidemic diseases is more optimistic.