参考文献 References
[1] Guarente L. Calorie restriction and sirtuins revisited[J].Genes Dev,2013;27
(19)
: 2072-2085.
[2] Jang J, Huh Y J, Cho H J, et al. SIRT1 Enhances the Survival of Human Embryonic Stem Cells by Promoting DNA Repair[J] .Stem Cell Reports,2017;9
(2)
: 629-641.
[3] Wang G, Wang F, Ren J, et al. SIRT1 Involved in the Regulation of Alternative Splicing Affects the DNA Damage Response in Neural Stem Cells[J].Cell Physiol Biochem,2018;48
(2)
: 657-669.
[4] Utani K, Aladjem M I. Extra View: Sirt1 Acts As A Gatekeeper Of Replication Initiation To Preserve Genomic Stability[J].Nucleus,2018;9
(1)
: 261-267.
[5] Ong A, Ramasamy T S. Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming[J].Ageing Res Rev,2018;43
: 64-80.
[6] Ghosh D, Bohr V A, Karmakar P. Acetylation of Werner protein at K1127 and K1117 is important for nuclear trafficking and DNA repair[J].DNA Repair (Amst),2019;79
: 22-31.
[7] Lin Y H, Yuan J, Pei H, et al. KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair[J].PLoS One,2015;10
(4)
: e123935.
[8] Utani K, Fu H, Jang S M, et al. Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability[J].Nucleic Acids Res,2017;45
(13)
: 7807-7824.
[9] Yasuda T, Kagawa W, Ogi T, et al. Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites[J].PLoS Genet,2018;14
(3)
: e1007277.
[10] Zhang H, Park S H, Pantazides B G, et al. SIRT2 directs the replication stress response through CDK9 deacetylation[J].Proc Natl Acad Sci U S A,2013;110
(33)
: 13546-13551.
[11] Onn L, Portillo M, Ilic S, et al. SIRT6 is a DNA double-strand break sensor[J].Elife,2020;9
.
[12] Atsumi Y, Minakawa Y, Ono M, et al. ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient gammaH2AX Foci Formation[J].Cell Rep,2015;13
(12)
: 2728-2740.
[13] Mao Z, Hine C, Tian X, et al. SIRT6 promotes DNA repair under stress by activating PARP1[J].Science,2011;332
(6036)
: 1443-1446.
[14] Hou T, Cao Z, Zhang J, et al. SIRT6 coordinates with CHD4 to promote chromatin relaxation and DNA repair[J].Nucleic Acids Res,2020;
.
[15] Tang M, Li Z, Zhang C, et al. SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair[J].Sci Adv,2019;5
(3)
.
[16] Song C, Hotz-Wagenblatt A, Voit R, et al. SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability[J].Genes Dev,2017;31
(13)
: 1370-1381.
[17] Rifai K, Judes G, Idrissou M, et al. SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylation in human breast cancer[J] .Oncotarget,2018;9
(55)
: 30661-30678.
[18] Serrano L, Martinez-Redondo P, Marazuela-DuqueA, et al . The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation[J].Genes Dev,2013;27
(6)
: 639-653.
[19] Michishita E, Mccord R A, Berber E, et al. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin[J].Nature,2008;452
(7186)
: 492-496.
[20] Tasselli L, Xi Y, Zheng W, et al. SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence[J].Nat Struct Mol Biol,2016;23
(5)
: 434-440.
[21] Li L, Shi L, Yang S, et al. SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability[J].Nat Commun,2016;7
: 12235.
[22] Bao X, Liu Z, Zhang W, et al. Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics[J].Mol Cell,2019;76
(4)
: 660-675.
[23] Zhao G, Cheng Y, Gui P, et al. Dynamic acetylation of the kinetochore-associated protein HEC1 ensures accurate microtubule-kinetochore attachment[J].J Biol Chem,2019;294
(2)
: 576-592.
[24] Ling H, Peng L, Wang J, et al. Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication[J].Cell Rep,2018;25
(10)
: 2851-2865.
[25] Kim H S, Vassilopoulos A, Wang R H, et al. SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity[J].Cancer Cell,2011;20
(4)
: 487-499.