The effect of bisoprolol fumarate on the treatment of elderly hypertension with cardiac dysfunction and its impact on the heart
富马酸比索洛尔治疗老年高血压伴心功能不全效果及对心脏的影响

摘要

目的 分析对老年高血压（HTN）伴心功能不全患者实施富马酸比索洛尔治疗的效果及对心脏的影响。方法 纳入60例HTN伴心功能不全患者为研究对象，均于2024年1月-2025年1月在我院进行治疗，通过掷硬币法将其分为对照组（n=30，常规治疗）、观察组（n=30，常规治疗+富马酸比索洛尔治疗）。持续治疗12周，比较治疗效果。结果 观察组血压、心功能以及血清因子等指标均优于对照组，比较均存在统计学差异（P<0.05）。结论 富马酸比索洛尔可有效控制老年HTN伴心功能不全患者血压，改善心脏收缩与舒张功能，降低心肌损伤相关血清因子水平，具有推广价值。

Abstract

Objective To analyze the effect of bisoprolol fumarate treatment on elderly patients with hypertension (HTN) and cardiac dysfunction, and its impact on the heart.
Methods Sixty patients with HTN accompanied by cardiac dysfunction were included as the study subjects, all of whom received treatment in our hospital from January 2024 to January 2025. They were divided into a control group (n=30, conventional treatment) and an observation group (n=30, conventional treatment + bisoprolol fumarate treatment) by flipping a coin. Continue treatment for 12 weeks and compare the therapeutic effects.
Results The blood pressure, heart function, and serum factors in the observation group were all better than those in the control group, and there were statistically significant differences (P<0.05).
Conclusion   Bisoprolol fumarate can effectively control blood pressure, improve systolic and diastolic function, and reduce serum factor levels related to myocardial injury in elderly patients with HTN and cardiac dysfunction, and has promotional value.