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临床护理进展

Journal of Advances in Clinical Nursing

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Journal of Advances in Clinical Nursing. 2026; 5: (10) ; 10.12208/j.jacn.20260535 .

Efficacy analysis of nasal high-flow oxygen therapy combined with non-invasive positive pressure ventilation in elderly patients with severe pneumonia and respiratory failure
经鼻高流量氧疗联合无创正压通气治疗对老年重症肺炎并呼吸衰竭患者的疗效分析

作者： 郭海星 *

郑州人民医院 河南郑州

*通讯作者： 郭海星,单位：郑州人民医院 河南郑州; ；

引用本文: 郭海星 经鼻高流量氧疗联合无创正压通气治疗对老年重症肺炎并呼吸衰竭患者的疗效分析[J]. 临床护理进展, 2026; 5: (10) : 97-99.
Published: 2026/10/6 9:22:45

摘要

目的 研究应用经鼻高流量氧疗联合无创正压通气为老年重症肺炎并呼吸衰竭患者所展现的临床效果和实际实施价值。方法 本次研究的观察对象均来自于2024年12月截止到2025年12月期间在我院收治护理的老年重症肺炎并呼吸衰竭患者，共计52例，根据随机自动抽签方法将其分为对照组和观察组，并对两组患者的生命体征指标、肺功能指标及并发症发生率进行观察统计分析。结果 观察组包括心率（HR）、呼吸频率（RR）、急性生理学与慢性健康状况评估Ⅱ评分（APACHE Ⅱ）在内的生命体征指标降低幅度更大，包括第1秒用力呼气容积（FEV1）、用力肺活量（FVC）、FEV1/FVC在内的肺功能指标改善效果更好，并发症发生率更低。组间数值P＜0.05，说明存在对比意义。结论 应用经鼻高流量氧疗联合无创正压通气为老年重症肺炎并呼吸衰竭患者对改善患者的临床疗效、生命体征指标、肺功能指标均有良好导向作用，减少患者并发症状的发生情况，提高患者满意程度，值得在临床上进行推广。

关键词： 经鼻高流量氧疗；无创正压通气；重症肺炎；呼吸衰竭

Abstract

Objective To investigate the clinical efficacy and practical value of combining transnasal high-flow oxygen therapy with non-invasive positive pressure ventilation in elderly patients with severe pneumonia and respiratory failure.
Methods The study enrolled 52 elderly patients with severe pneumonia and respiratory failure admitted to our hospital from December 2024 to December 2025. These patients were randomly divided into a control group and an observation group by random automatic drawing method. Vital signs, pulmonary function parameters, and complication rates were statistically analyzed between the two groups.
Results The observation group showed greater reductions in vital signs [Heart Rate (HR), Respiratory Rate (RR), Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE II) scores], better improvements in pulmonary function parameters [Forced expiratory volume in 1 second (FEV1), Forced vital capacity (FVC), FEV1/FVC ratios], and lower complication rates compared to the control group (P <0.05).
Conclusion   The combination of transnasal high-flow oxygen therapy with non-invasive positive pressure ventilation demonstrates significant benefits for improving clinical outcomes, stabilizing vital signs, enhancing pulmonary function, reducing complications, and increasing patient satisfaction in elderly patients with severe pneumonia and respiratory failure, It is worthy of clinical promotion.

Key words： Transnasal high-flow oxygen therapy; Non-invasive positive pressure ventilation; Severe pneumonia; Respiratory failure

参考文献 References

[1] Yang F ,Zhong Y ,Yu Q . High-flow nasal cannula and interface- or mode-specific noninvasive ventilation in acute hypoxemic respiratory failure: an endpoint-harmonized systematic review and Bayesian network meta-analysis of randomized trials[J].MEDS Clinical Medicine,2026,7 (2)

[2] Hu J ,Qiu Z ,Xia D , et al. Comparison of high-flow nasal cannula oxygen therapy versus nasal cannula in sedated transoesophageal echocardiography in patients with mitral regurgitation: a prospective, randomized controlled clinical trial.[J].Journal of cardiothoracic surgery,2026.

[3] 邓江,陈丰勤. 无创呼吸机联合经鼻高流量氧疗序贯治疗对重症肺炎合并呼吸衰竭患者的治疗效果分析[J].基层医学论坛,2026,30 (7):53-55+143.

[4] 林晓扬. HFNC与NIPPV通气策略在重症肺炎合并呼吸衰竭患者中的应用对比[J].黑龙江医学,2026,50 (2):151-154.

[5] 马利利,柳光春,李莹. 无创正压机械通气联合经鼻高流量氧疗治疗重症肺炎合并呼吸衰竭的研究[J].临床研究,2025,33 (10):33-36.

[6] 赵鹏林,赵锐艳,谢方方,等. 经鼻高流量氧疗联合盐酸氨溴索治疗老年重症肺炎合并呼吸衰竭对患者肺功能及炎性反应的影响[J].临床合理用药,2025,18 (26):60-63.

[7] 张坤,朱进,张华. 有创机械通气序贯经鼻高流量氧疗对重症肺炎合并呼吸衰竭患者的治疗效果[J].世界复合医学(中英文),2025,11 (8):128-133.

[8] 申洁,韦存兄,武雪,等.经面罩无创正压通气与经鼻高流量湿化氧疗对病毒性肺炎所致急性呼吸窘迫综合征患者气管插管率的影响[J].中华危重病急救医学,2025,37(11):1013-1018.

[9] 袁广胜,陈万宏. 经鼻高流量氧疗与无创正压通气交替使用治疗老年重症肺炎并呼吸衰竭患者的临床效果[J].临床医学研究与实践,2024,9 (29):63-66.