Analysis of the efficacy and safety of intravenous thrombolysis in elderly patients with acute cerebral infarction
老年急性脑梗死患者静脉溶栓的疗效及安全性分析

摘要

目的 分析老年急性脑梗死患者行静脉溶栓治疗的效果及安全性。方法 将2021年10月-2025年6月接收的62例老年急性脑梗死患者纳入研究，随机分为研究组与参照组，每组31例。参照组采取传统方法治疗，研究组采取静脉溶栓治疗，对比两组血管分级率、治疗前后的脑血管指标水平和不良反应出现率。结果 研究组血管3级率高于参照组（P＜0.05），两组血管0、1、2级率均接近（P＞0.05）；治疗前，两组脑血管指标水平均较低（P＞0.05），治疗后，两组脑血管指标水平均提高，研究组高于参照组（P＜0.05）；研究组不良反应出现率低于参照组（P＜0.05）。结论 老年急性脑梗死患者行静脉溶栓治疗具有显著效果和较高的安全性。

Abstract

Objective To analyze the efficacy and safety of intravenous thrombolysis in elderly patients with acute cerebral infarction.
Methods A total of 62 elderly patients with acute cerebral infarction admitted from October 2021 to June 2025 were included in the study and randomly divided into the study group and the reference group, with 31 cases in each group. The reference group received traditional treatment, while the study group received intravenous thrombolysis. The vascular grade rate, the levels of cerebrovascular indicators before and after treatment, and the incidence of adverse reactions were compared between the two groups.
Results The rate of vascular grade 3 in the study group was higher than that in the reference group (P < 0.05), and the rates of vascular grades 0, 1, and 2 in both groups were similar (P > 0.05); Before treatment, the levels of cerebrovascular indicators in both groups were low (P > 0.05), and after treatment, the levels of cerebrovascular indicators in both groups increased, with the study group higher than the reference group (P < 0.05); The incidence of adverse reactions in the study group was lower than that in the reference group (P < 0.05).
Conclusion   Intravenous thrombolysis in elderly patients with acute cerebral infarction has significant efficacy and high safety.