Analysis of the role of MRI multimodal imaging in the diagnosis of hepatocellular carcinoma
MRI多模态成像在肝细胞肝癌诊断中的作用分析

摘要

目的 通过对磁共振多模态成像技术应用于肝细胞肝癌诊断的研究探索磁共振成像在发现、区分良恶性病灶以及判断病灶进展程度方面的特殊作用。方法 将怀疑有肝细胞肝癌的病人作为研究样本，在常规磁共振成像（MRI）平扫、动态增强扫描、弥散加权成像（DWI）、表观弥散系数（ADC）、灌注加权序列等方面加以观察，通过图像分析得出肿瘤大小、血运和细胞内水分变化情况，并与病理诊断或者病情跟踪结果相比较。结果 通过磁共振多模态影像学检查可以明确地呈现出肝细胞肝癌的解剖结构、供血来源及内部组织分化状态；对小病灶的识别率也相对较高。动态增强对于肿瘤动脉期高灌注、门静脉期及延迟期廓清以及典型特征鉴别较佳，DWI及ADC值对于鉴别可疑病灶有着更好的辅助作用。多模态影像对比可以更好地对肿瘤边缘检测、子病灶寻找以及血管侵犯情况做出判定。结论 MRI多模态成像是基于影像学对肝细胞性肝癌进行从形态、血流动力学和组织扩散等多个层面的分析判断，具有较高的诊断意义和临床应用价值，可用于早期发现、准确诊断以及治疗计划的选择。

Abstract

Objective Through the research on the application of magnetic resonance multimodal imaging technology in the diagnosis of hepatocellular carcinoma, this study explores the special role of magnetic resonance imaging in detecting, differentiating benign and malignant lesions, and judging the progression of the lesion.
Methods Patients suspected of having hepatocellular carcinoma were selected as the research samples. The conventional Magnetic Resonance Imaging (MRI) plain scan, dynamic enhancement scan, diffusion weighted imaging (DWI), apparent diffusion coefficient (ADC), and perfusion weighted sequence were observed. Through image analysis, the tumor size, blood supply, and changes in intracellular water were obtained, and compared with the pathological diagnosis or follow-up results.
Results Through multimodal magnetic resonance imaging examination, the anatomical structure, blood supply source, and internal tissue differentiation status of hepatocellular carcinoma can be clearly presented; the recognition rate of small lesions is also relatively high. Dynamic enhancement is better for the high perfusion of the tumor during the arterial phase, the clearance during the portal venous phase and the delayed phase, and the identification of typical features. DWI and ADC values have better auxiliary effects for differentiating suspicious lesions. The comparison of multimodal imaging can better determine the tumor edge detection, sub-tumor finding, and vascular invasion situation.
Conclusion   MRI multimodal imaging is based on imaging to analyze and judge hepatocellular carcinoma from multiple aspects such as morphology, hemodynamic, and tissue diffusion. It has high diagnostic significance and clinical application value and can be used for early detection, accurate diagnosis, and selection of treatment plans.