Efficacy analysis of three-dimensional conformal radiotherapy combined with chemotherapy in the treatment of local recurrence of lung cancer
三维适形放疗联合化疗治疗肺癌局部复发的疗效分析

摘要

目的 观察不同方案医治肺癌局部复发的效果。方法 选取2024年4月-2025年8月我科室收治的70例患者病历资料展开分析，对照组35例患者接受常规放射治疗，对观察组35例患者行三维适形放疗（3-DCRT）+化疗治疗方案，对比两组患者的治疗结局。结果 在总有效率上，观察组vs.对照组为85.71% vs.51.43%，差异有统计学意义（P＜0.05）。治疗过程中，组间患者毒性反应发生率相近，即差异不显著（P＞0.05）。结论 对肺癌局部复发患者行3-DCRT联合化疗治疗，和单纯放疗相比较，能更好的控制病情，且基本不会增加不良反应发生率，远期疗效较好，值得推广。

Abstract

Objective To observe the efficacy of different treatment regimens for local recurrence of lung cancer.
Methods The medical records of 70 patients admitted to our department from April 2024 to August 2025 were selected for analysis. The control group included 35 patients who received conventional radiotherapy, while the observation group consisted of 35 patients who underwent three-dimensional conformal radiotherapy (3-DCRT) + chemotherapy treatment. The treatment outcomes of the two groups were compared.
Results In terms of overall effectiveness, the observation group vs. the control group was 85.71% vs. 51.43%, and the difference was statistically significant (P<0.05). During the treatment process, the incidence of toxic reactions in patients between the groups was similar, that is, the difference was not significant (P>0.05).
Conclusion   For patients with local recurrence of lung cancer, the treatment with 3-DCRT combined with chemotherapy is better at controlling the condition compared to simple radiotherapy, and it does not significantly increase the incidence of adverse reactions, with better long-term efficacy. It is worthy of promotion.