Therapeutic effect of different blood purification nursing models on patients with uremia
不同血液净化护理模式对尿毒症患者的治疗效果

摘要

目的 探讨常规护理与综合优质护理两种模式在尿毒症血液净化治疗中的应用效果。方法 选取我院2024年5月至2025年5月收治的尿毒症行血液净化治疗患者60例，随机分为对照组与观察组各30例。对照组采用血液净化常规护理模式，观察组在常规护理基础上实施综合优质护理干预。比较两组肾功能与代谢指标、透析充分性指标、并发症发生率及生活质量评分。结果 干预后，观察组血尿素氮、血肌酐、β2微球蛋白、血磷水平低于对照组，血清白蛋白、血钙水平均高于对照组；观察组透析充分性指数、尿素清除指数达标率高于对照组；相较对照组，观察组并发症发生率更低；观察组在健康调查简表（Short Form 36 Health Survey , SF-36）各维度生存质量改善效果均优于对照组（P＜0.05）。结论 综合优质护理应用于尿毒症血液净化患者，可显著提升毒素清除效果、改善营养与电解质代谢、降低并发症风险、提高透析充分性与生活质量，临床推广价值显著。

Abstract

Objective To investigate the application effects of conventional nursing and comprehensive high-quality nursing in hemodialysis treatment for uremia.
Methods A total of 60 patients with uremia undergoing hemodialysis treatment admitted to our hospital from May 2024 to May 2025 were selected and randomly divided into a control group and an observation group, with 30 cases in each group. The control group received conventional hemodialysis nursing, while the observation group received comprehensive high-quality nursing intervention in addition to conventional nursing. The renal function and metabolic indicators, dialysis adequacy indicators, complication incidence rates, and quality of life scores were compared between the two groups.
Results After the intervention, the levels of blood urea nitrogen, creatinine, β 2-microglobulin, and phosphorus in the observation group were lower than those in the control group, while the levels of serum albumin and blood calcium were higher than those in the control group; The compliance rates of dialysis adequacy index and urea clearance index in the observation group were higher than those in the control group; Compared to the control group, the observation group had a lower incidence of complications; The observation group showed better improvement in quality of life in all dimensions of the Health Survey Brief (SF-36) compared to the control group (P<0.05).
Conclusion   The application of comprehensive high-quality nursing in hemodialysis patients with uremia can significantly enhance toxin clearance, improve nutritional and electrolyte metabolism, reduce complication risks, and improve dialysis adequacy and quality of life, demonstrating significant clinical promotion value.