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现代护理医学杂志

Journal of Modern Nursing Medicine

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Journal of Modern Nursing Medicine. 2026; 5: (5) ; 10.12208/j.jmnm.20260239 .

The impact of multidisciplinary collaborative nursing model on thrombosis risk and quality of life in breast cancer patients undergoing chemotherapy
多学科协作护理模式对乳腺癌化疗患者血栓风险及生活质量的影响

作者： 李平 *, 颜文静

华中科技大学同济医学院附属同济医院甲乳外科 湖北武汉

*通讯作者： 李平,单位：华中科技大学同济医学院附属同济医院甲乳外科 湖北武汉; ；

引用本文: 李平, 颜文静 多学科协作护理模式对乳腺癌化疗患者血栓风险及生活质量的影响[J]. 现代护理医学杂志, 2026; 5: (5) : 24-27.
Published: 2026/5/16 9:00:43

摘要

目的 探讨多学科协作（MDT）护理模式对乳腺癌化疗患者血栓发生风险及生活质量的影响。方法选取2025年本院100例乳腺癌化疗患者，随机分为对照组和研究组各50例。对照组常规护理，研究组加用多学科协作护理。比较两组血栓发生率、凝血指标（D-二聚体、纤维蛋白原、APTT），采用QLQ-C30和QLQ-BR45评估生活质量，记录护理满意度和不良事件。结果 研究组血栓发生率（4.00%）显著低于对照组（16.00%）。研究组D-二聚体、纤维蛋白原水平低于对照组，活化部分凝血活酶时间更长。研究组生活质量评分及护理满意度（96.00%）均高于对照组（82.00%），两组不良事件发生率无显著差异。结论 多学科协作护理模式可有效降低乳腺癌化疗患者血栓风险，改善凝血功能，提升生活质量及护理满意度，安全性良好，值得临床推广。

关键词： 多学科协作护理；乳腺癌；化疗；血栓风险；生活质量

Abstract

Objective To explore the impact of multidisciplinary collaboration (MDT) nursing model on the thrombosis risk and quality of life of breast cancer patients undergoing chemotherapy.
Methods 100 breast cancer patients undergoing chemotherapy in our hospital in 2025 were selected and randomly divided into a control group and a study group, with 50 cases in each group. The control group received routine care, while the study group received additional multidisciplinary collaboration care. The incidence of thrombosis, coagulation indicators (D-dimer, fibrinogen, APTT), quality of life were compared using QLQ-C30 and QLQ-BR45, and the nursing satisfaction and adverse events were recorded.
Results The incidence of thrombosis in the study group (4.00%) was significantly lower than that in the control group (16.00%). The levels of D-dimer and fibrinogen in the study group were lower than those in the control group, and the activated partial thromboplastin time was longer. The quality of life score and nursing satisfaction (96.00%) of the study group were higher than those of the control group (82.00%), and there was no significant difference in the incidence of adverse events between the two groups.
Conclusion   The multidisciplinary collaboration nursing model can effectively reduce the thrombosis risk of breast cancer patients undergoing chemotherapy, improve coagulation function, enhance quality of life and nursing satisfaction, with good safety, and is worthy of clinical promotion.

Key words： Multidisciplinary collaboration nursing; Breast cancer; Chemotherapy; Thrombosis risk; Quality of life

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