Observation and intervention strategies for adverse reactions in patients undergoing radiotherapy combined with immunotherapy
放疗联合免疫治疗患者不良反应的护理观察与干预策略

摘要

目的 分析放疗联合免疫治疗肿瘤患者不良反应的特征，评估护理干预对改善患者症状的效果。方法 选取我院2024年5月至2025年5月期间66例接受放疗联合免疫治疗的患者，实施一套综合性护理干预。比较护理前后各指标变化。结果 干预后患者≥3级不良反应总发生率明显下降，患者整体生活质量评分显著提升，焦虑与抑郁评分也明显下降（P<0.05）。结论 针对放疗联合免疫治疗患者实施系统化护理，能有效降低中重度不良反应的发生率，提升其生活质量。

Abstract

Objective To analyze the characteristics of adverse reactions in patients with tumors undergoing radiotherapy combined with immunotherapy, and to evaluate the effect of nursing intervention on improving patients' symptoms.
Methods 66 patients who received radiotherapy combined with immunotherapy in our hospital from May 2024 to May 2025 were selected. A comprehensive nursing intervention was implemented. The changes in various indicators before and after the intervention were compared.
Results After the intervention, the total incidence of grade 3 or above adverse reactions in patients significantly decreased, and the overall quality of life score of patients significantly improved, and the anxiety and depression scores also significantly decreased (P < 0.05).
Conclusion   Implementing systematic nursing for patients undergoing radiotherapy combined with immunotherapy can effectively reduce the incidence of moderate to severe adverse reactions and improve their quality of life.