Efficacy analysis of modified Yinchenhao Decoction combined with auricular bloodletting for spleen-stomach damp-heat type rosacea based on traditional Chinese medicine constitution theory
加味茵陈蒿汤联合耳尖放血干预脾胃湿热型玫瑰痤疮中医证候的临床研究

摘要

目的 本研究旨在评估基于中医证候的加味茵陈蒿汤联合耳尖放血对脾胃湿热型玫瑰痤疮的干预效果，为该类型玫瑰痤疮的综合治疗方案提供实证依据。方法 选取2025年7月至2026年1月某医学院校的50例脾胃湿热型玫瑰痤疮患者，按随机数字表分配法，将50名患者分为两组，治疗组、对照组分别25人，治疗组接受加味茵陈蒿汤与耳尖放血联合干预，对照组只用加味茵陈蒿汤干预。干预周期为6周，干预前后通过皮肤病生活质量指数（DLQI）、中医证候评分、自觉症状评分进行评估，比较两组间的治疗效果。结果 治疗组在皮肤病生活质量指数（DLQI）显著下降（P<0.05），改善幅度明显优于对照组。中医症候评分疗效标准显示治疗组脾胃湿热症候得到显著改善（P<0.01），自觉症状评分也较对照组显著降低（P<0.01）。此外，治疗组在玫瑰痤疮皮损症状改善和脾胃湿热症候改善两方面表现出显著疗效。结论 基于中医症候的加味茵陈蒿汤联合耳尖放血对脾胃湿热型玫瑰痤疮具有显著的干预效果，对调整患者的皮肤状态、体质状态和缓解炎症等都有非常显著的效果，为脾胃湿热型玫瑰痤疮的综合治疗提供了一种有效的治疗方案。

Abstract

Objective This study aims to evaluate the intervention effect of modified Yinchenhao Decoction combined with auricular point bleeding based on Traditional Chinese Medicine (TCM) syndrome patterns on rosacea of damp-heat type in the spleen and stomach, and to provide empirical evidence for the comprehensive treatment plan of this type of rosacea.
Methods A total of 50 patients with rosacea of the spleen-stomach damp-heat type from a medical college between July 2025 and January 2026 were selected. According to the random number table allocation method, the 50 patients were divided into two groups: the treatment group and the control group, with 25 patients in each group. The treatment group received the combined intervention of Modified Yinchenhao Decoction and auricular puncture bleeding, while the control group received only Modified Yinchenhao Decoction. The intervention period was 6 weeks. The treatment effects were assessed before and after the intervention using the Dermatology Life Quality Index (DLQI), TCM syndrome score, and subjective symptom score, and the therapeutic effects between the two groups were compared.
Results The treatment group showed a significant decrease in the Dermatology Life Quality Index (DLQI) (P<0.05), with a significantly better improvement than the control group. The TCM syndrome score indicated that the treatment group achieved significant improvement in the spleen-stomach damp-heat syndrome(P<0.01), and the subjective symptom score was also significantly lower than that of the control group(P<0.01). Additionally, the treatment group demonstrated significant therapeutic effects in both the improvement of rosacea skin lesions and the improvement of spleen-stomach damp-heat syndrome.
Conclusion   The combination of Modified Yinchenhao Decoction and auricular puncture bleeding based on TCM syndrome has a significant intervention effect on rosacea of the spleen-stomach damp-heat type, showing very significant effects in adjusting the patient's skin condition, constitution, and alleviating inflammation, providing an effective treatment plan for the comprehensive management of this type of rosacea.