Clinical efficacy analysis of Xuanbai Chengqi decoction in patients with severe pneumonia cough based on phlegm-heat congestion to lung type
基于痰热壅肺型重症肺炎咳嗽患者应用宣白承气汤的临床疗效分析

摘要

目的 重点探讨宣白承气汤辅助治疗痰热壅肺型重症肺炎咳嗽患者的临床价值，总结分析其对疾病疗效、咳嗽症状缓解进程及炎症因子水平的影响。方法 纳入近两年来临床确诊为痰热壅肺型重症肺炎、以咳嗽为主要症状的患者60例，采用随机分配原则划分为对照组与观察组，每组各30例，确保组间基线特征均衡可比。并在各组分别开展常规西医治疗（对照组）及宣白承气汤治疗（观察组），两组治疗后的临床疗效、咳嗽症状缓解时间、炎症因子（PCT、IL-6、CRP）水平各项针对性比较。结果 观察组总有效率高于对照组（P<0.05），咳嗽缓解时间观察组短于对照组（P<0.05）；治疗后PCT、IL-6、CRP水平观察组低于对照组（P<0.05）。结论 宣白承气汤辅助治疗痰热壅肺型重症肺炎咳嗽患者，能提高疗效，缩短咳嗽缓解时间，降低炎症因子水平，改善患者病情。

Abstract

Objective To focus on exploring the clinical value of Xuanbai Chengqi Decoction in the auxiliary treatment of cough patients with severe pneumonia caused by phlegm-heat congestion in the lungs, and to summarize and analyze its influence on the disease efficacy, the process of cough symptom relief, and the levels of inflammatory factors.
Methods Sixty patients clinically diagnosed with severe pneumonia of phlegm-heat congestion lung type in the past two years, with cough as the main symptom, were included. They were randomly divided into the control group and the observation group according to the principle of random allocation, with 30 cases in each group, to ensure balanced and comparable baseline characteristics between the groups. Conventional Western medical treatment (control group) and Xuanbai Chengqi Decoction treatment (observation group) were carried out separately in each group. Targeted comparisons were made in terms of clinical efficacy, relief time of cough symptoms, and levels of inflammatory factors (PCT, IL-6, CRP) after treatment between the two groups.
Results The total effective rate of the observation group was higher than that of the control group (P<0.05), and the cough relief time of the observation group was shorter than that of the control group (P<0.05). After treatment, the levels of PCT, IL-6 and CRP in the observation group were lower than those in the control group (P<0.05).
Conclusion   Xuanbai Chengqi Decoction as an adjunctive treatment for patients with severe pneumonia cough caused by phlegm-heat congestion in the lungs can enhance the therapeutic effect, shorten the time for cough relief, reduce the levels of inflammatory factors, and improve the patient's condition.