International Journal of Clinical Research
International Journal of Clinical Research. 2026; 10: (2) ; 10.12208/j.ijcr.20260073 .
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1 湛江久和医院男科 广东湛江
2 长江大学附属第一医院 湖北荆州
3 巴州人民医院 新疆维吾尔自治区巴音郭楞蒙古自治州
4 周口市中心医院男性病科 河南周口
5 华中科技大学同济医学院生殖医学中心 湖北武汉
*通讯作者： 熊承良,单位： 华中科技大学同济医学院生殖医学中心 湖北武汉；
目的 观察磁刺激联合生物反馈对比单纯磁刺激治疗慢性前列腺炎/慢性盆腔疼痛综合征（CP/CPPS）的临床疗效及差异，为联合物理治疗方案提供循证依据。方法 采用多中心随机对照设计，将60例NIH-ⅢB型CP/CPPS患者按1:1随机分为两组。对照组接受单纯磁刺激（20分钟/次），观察组接受磁刺激联合生物反馈（共30分钟/次）。两组均接受每周2-3次、共10次治疗。主要结局指标包括治疗前后美国国立卫生研究院慢性前列腺炎症状指数、盆底运动水平、国际勃起功能问卷-5、早泄诊断量表及国际前列腺症状评分；次要指标为治疗后1个月随访时的上述量表评分。采用盲态评估与意向性分析处理数据。结果 预期联合治疗组在改善疼痛、排尿症状、性功能等方面优于单纯磁刺激组，且疗效可持续。结论 磁刺激联合生物反馈可能通过主被动协同作用更有效缓解CP/CPPS症状、改善盆底功能，为非药物个体化治疗提供新选择。
Objective This study aimed to compare the clinical efficacy of magnetic stimulation combined with biofeedback versus magnetic stimulation alone in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and to provide evidence-based support for combined physiotherapy regimens. Methods A multicenter randomized controlled trial was conducted. Sixty patients diagnosed with NIH-ⅢB CP/CPPS were randomly allocated (1:1) to two groups. The control group received magnetic stimulation alone (20 minutes per session), while the observation group received magnetic stimulation combined with biofeedback (30 minutes per session). Both groups received treatment 2-3 times per week, for a total of 10 sessions. Primary outcome measures included changes in the NIH Chronic Prostatitis Symptom Index, pelvic floor muscle function, the International Index of Erectile Function-5, the Premature Ejaculation Diagnostic Tool, and the International Prostate Symptom Score. Secondary outcomes were the scores of these scales at the 1-month follow-up. Blinded assessment and intention-to-treat analysis were employed. Results It is expected that the combined therapy group will demonstrate superior improvements in pain, urinary symptoms, and sexual function compared to the magnetic stimulation-only group, with sustained therapeutic effects. Conclusion Magnetic stimulation combined with biofeedback may alleviate CP/CPPS symptoms and enhance pelvic floor function more effectively through synergistic active and passive mechanisms, offering a new non-pharmacological option for individualized treatment.
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