Study on the efficacy and safety of laparoscopic appendectomy in the treatment of acute appendicitis
腹腔镜下阑尾切除术在急性阑尾炎治疗中的疗效及安全性研究

摘要

目的 分析急性阑尾炎治疗中腹腔镜下阑尾切除术的价值。方法 以120例急性阑尾炎患者为样本，按奇偶法分组，一般组、研究组各60例，一般组行开放性手术，研究组行腹腔镜下阑尾切除术，均于2014年9月-2024年9月入选，比较恢复情况，分析炎症因子，评估安全性。结果 下床时间、肠鸣音恢复时间、初次排气以及排便时间较短的是研究组，较长的是一般组，术后12hNRS评分较低的是研究组，较高的是一般组，P<0.05。术前CRP、WBC、中性粒细胞比例在研究组、一般组差异不大，P>0.05；术后24h的CRP、WBC、中性粒细胞比例均有明显降幅，组间比较时，偏低的是研究组，偏高的是一般组，P<0.05。经并发症分析各组的安全性，发生率偏低的是研究组（3.33%，2/60），偏高的是一般组（16.67%，10/60），P<0.05。结论 腹腔镜阑尾切除术实施后，急性阑尾炎患者的恢复周期会明显缩短，疼痛会迅速减轻，并发症也比较少，且炎症刺激较轻微，有推广意义。

Abstract

Objective To analyze the value of laparoscopic appendectomy in the treatment of acute appendicitis.
Methods A total of 120 patients with acute appendicitis were selected and divided into two groups according to odd-even numbering, with 60 cases in the general group and 60 cases in the study group. The general group underwent open surgery, while the study group underwent laparoscopic appendectomy. All patients were enrolled from September 2014 to September 2024. Recovery outcomes were compared, inflammatory factors were analyzed, and safety was evaluated.
Results The study group had shorter times for getting out of bed, bowel sound recovery, first flatus, and defecation, while these times were longer in the general group. The NRS scores 12 hours postoperatively were lower in the study group and higher in the general group, P<0.05. The preoperative CRP, WBC, and neutrophil ratio showed little difference between the study group and the general group, P>0.05; 24 hours after surgery, there was a significant decrease in CRP, WBC, and neutrophil ratio. When comparing between groups, the study group had a lower level, while the general group had a higher level, P<0.05. Safety analysis based on complications showed a lower incidence in the study group (3.33%, 2/60) and a higher incidence in the general group (16.67%, 10/60), P<0.05.
Conclusion   After laparoscopic appendectomy, patients with acute appendicitis experience a significantly shorter recovery period, rapid pain relief, fewer complications, and milder inflammatory stimulation, indicating its potential for wider application.