Analysis of the effect of hemoperfusion on pruritus in hemodialysis patients
血液灌流对血液透析患者瘙痒症影响分析

摘要

目的 调查血液灌流对血液透析患者瘙痒症影响分析。方法 随机抽选的106例血液透析的肾脏病患者，均为宁夏医科大学总医院肾脏内科血液透析中心治疗者，研究时间2023年1月至2023年11月，采用尿毒症皮肤瘙痒量表进行评分，判断瘙痒症发生率,同时进行对比分组，第一组以透析处方1血透透析+血液透析滤过，处方2血透透析+血液透析滤过+血液灌流分组，两组透析模式与瘙痒状况分析；第二组在前两组的基础上进行透析模式与瘙痒评分分析。结果 本研究共纳入106例有效血液透析患者数据。1与血液灌流组的患者相比，非血液灌流组的患降到者瘙痒时间更长（p=0.0419）、瘙痒面积占人体体表面积更大（p=0.0062）、皮肤干燥程度更重（p=0.0001）；2血液灌流组患者中度瘙痒比例低于非血液灌流组患者。结论 血液灌流改善了血液透析患者瘙痒症状，降低了中度瘙痒发生率。

Abstract

Objective To investigate the impact of blood perfusion on pruritus in hemodialysis patients.
Methods A total of 106 kidney disease patients undergoing hemodialysis were randomly selected and treated at the Hemodialysis Center of the Nephrology Department of Ningxia Medical University General Hospital. The study period was from January 2023 to November 2023, and the Uremic Skin Itching Scale was used to score and determine the incidence of pruritus. At the same time, a comparative grouping was conducted. The first group was divided into dialysis prescription 1 hemodialysis+hemofiltration, prescription 2 hemodialysis+hemofiltration+hemoperfusion groups, and the dialysis mode and pruritus status of the two groups were analyzed; The second group conducted dialysis mode and itching score analysis based on the first two groups.
Results This study included data from 106 effective hemodialysis patients. Compared with patients in the hemoperfusion group, those in the non hemoperfusion group had a longer duration of itching (p=0.0419), a larger area of itching on the body surface (p=0.0062), and a more severe degree of skin dryness (p=0.0001); The proportion of patients with moderate itching in the hemoperfusion group was lower than that in the non hemoperfusion group.
Conclusion   Blood perfusion improves itching symptoms in hemodialysis patients and reduces the incidence of moderate itching.