International Journal of Nursing Research
International Journal of Nursing Research. 2026; 8: (1) ; 10.12208/j.ijnr.20260009 .
总浏览量: 68
同济大学附属东方医院肝胆胰外科、同济大学医学院肝胆胰外科研究所 上海
*通讯作者： 蒋芹芹,单位：同济大学附属东方医院肝胆胰外科、同济大学医学院肝胆胰外科研究所 上海；
目的 探讨5%碳酸氢钠溶液对预防鼻空肠营养管堵塞的作用，及分析造成鼻空肠营养管堵塞的风险因素。方法 收集2021年1月份至2025年7月份于上海市东方医院肝胆胰外科住院手术后留置鼻空肠营养管时间超过10天的病例，共36例。根据冲管液性质分成碳酸氢钠溶液组和生理盐水组进行对比分析。进一步采用单因素和多因素logistic回归分析的方法分析造成鼻空肠管堵塞堵塞的相关危险因素。结果 在纳入的36例患者中，生理盐水组堵塞发生率为39.1%（9/23），显著高于碳酸氢钠溶液组的7.7%（1/13），差异具有统计学意义（P<0.05）。多因素分析显示经营养管输注药物使堵塞风险增加9.346倍（95%CI:1.312-66.667）。结论 在经过鼻空肠营养管输注肠内营养时，应尽量使用碳酸氢钠溶液冲洗管道，可有效避免营养管梗阻。同时在必须经鼻空肠营养管注入的药物时，应该严格按照规范操作，避免堵塞管道。
Objective To investigate the efficacy of 5% sodium bicarbonate solution in preventing nasojejunal feeding tube blockage and analyze the risk factors associated with tube occlusion. Methods From January 2021 to July 2025, a total of 36 patients with nasojejunal nutrition tubes retained for more than 10 days after surgery in the Department of Hepatobiliary and Pancreatic Surgery of Shanghai East Hospital were included in this study. According to the properties of the flushing fluid, they were divided into the sodium bicarbonate solution group and the physiological saline group for comparative analysis. Further, univariate and multivariate logistic regression analysis methods were adopted to analyze the related risk factors causing nasojejunal tube obstruction. Results Among the 36 included patients, the incidence of blockage in the normal saline group was 39.1% (9/23), significantly higher than 7.7% (1/13) in the sodium bicarbonate solution group, and the difference was statistically significant (P<0.05). Multivariate analysis showed that the administration and maintenance of drugs increased the risk of blockage by 9.346 times (95%CI:1.312-66.667). Conclusion When infusing enteral nutrition through a nasojejunal nutrition tube, it is advisable to flush the tube with sodium bicarbonate solution, which can effectively prevent the obstruction of the nutrition tube. Moreover, when drugs must be injected through the nasojejunal nutrition tube, the operation should be carried out strictly in accordance with the norms to avoid blocking the tube.
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