Evaluation of the preventive effect and safety of the Tibetan medicine Five-Ingredient Arnebia Oil protective regimen for high-risk patients with Incontinence-Associated Dermatitis
藏医五味紫草油防护方案对失禁性皮炎高危人群的预防效果及安全性评价

摘要

目的 分析藏医五味紫草油防护方案对失禁性皮炎高危人群的预防效果，并探究其安全性。方法 采用回顾性研究方式，将2024年3月至2025年3月我院收治的具有失禁性皮炎高危风险的患者80例作为研究对象，会阴皮肤评估工具评估失禁性皮炎风险。按照干预手段的不同分为常规组与干预组，均40例。常规组接受常规干预手段，干预组在常规组基础上给予藏医五味紫草油防护。比较两组患者失禁性皮炎发生率、皮肤舒适度与生活质量、失禁性皮炎发生天数与转归时间、满意度。结果 与常规组比较，干预组患者失禁性皮炎发生率明显较低，满意度明显较高；失禁性皮炎发生天数与转归时间在两组间比较，干预组明显缩短；与干预前比较，干预后两组患者皮肤舒适度、SF-36评分均升高，且干预组高于常规组（P<0.05）。两组患者均未发生明显不良反应，具有较高的安全性。结论 藏医五味紫草油防护方案对失禁性皮炎高危人群具有良好的预防效果，降低该病的发生率，且对于已发生失禁性皮炎的患者，能缩短发生天数与转归时间，同时提高患者皮肤舒适度、生活质量与满意度，具有较高的安全性。

Abstract

Objective To analyze the preventive effect of Tibetan medicine Five-Ingredient Arnebia Oil protective regimen on high-risk incontinent patients for incontinence-associated dermatitis (IAD) and investigate its safety.
Methods A retrospective study was conducted on 80 patients at high risk for IAD admitted to our hospital from March 2024 to March 2025. The perineal skin assessment tool was used to evaluate IAD risk. According to different intervention methods, the patients were divided into a conventional group and an intervention group, with 40 cases in each group. The conventional group received conventional interventions, while the intervention group received the Tibetan medicine Five-Ingredient Arnebia Oil protective regimen in addition to the conventional care. The incidence of IAD, skin comfort and quality of life, time to onset and resolution of IAD, and satisfaction were compared between the two groups.
Results Compared with the conventional group, the intervention group had a significantly lower incidence of IAD and significantly higher satisfaction; the time to onset and resolution of IAD were significantly shorter in the intervention group. Compared with pre-intervention levels, the skin comfort and SF-36 scores increased in both groups after the intervention, and the scores in the intervention group were higher than those in the conventional group (P < 0.05). No significant adverse reactions occurred in either group, indicating high safety.
Conclusion   The Tibetan medicine Five-Ingredient Arnebia Oil protective regimen has a good preventive effect on high-risk individuals for IAD, reducing the incidence of the condition. For patients who have already developed IAD, it can shorten the time to onset and resolution, while also improving skin comfort, quality of life, and satisfaction, demonstrating high safety.