International Journal of Clinical Research
International Journal of Clinical Research. 2025; 9: (11) ; 10.12208/j.ijcr.20250545 .
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1 义乌市妇幼保健院药剂科 浙江义乌
2 义乌市妇幼保健院院部 浙江义乌
3 义乌市妇幼保健院院感科 浙江义乌
*通讯作者： 陈拥军,单位： 义乌市妇幼保健院院部 浙江义乌；
目的 分析信息闭环化管理在促进新生儿肠外营养制剂安全使用的作用。方法 回顾分析义乌市妇幼保健院药剂科2023年1月-2023年10月静脉药物调配中心2883张肠外营养液处方情况，为信息闭环管理实施前，设定为对照组；2024年1月-2024年10月静脉药物调配中心3402张肠外营养液处方情况，为信息闭环管理实施后，设定为观察组。对比信息闭环管理模式实施前后肠外营养制剂使用情况。结果 （1）观察组差错率显著低于对照组（P<0.05）为差异显著，有统计学意义。（2）新生儿肠外营养制剂使用流程中存在医嘱开立错误、处方审核错误、摆药错误、药品调配错误、成品核对错误、打包运输错误、腕带与药品信息不符等情况。观察组医嘱开立错误、处方审核错误、摆药错误、药品调配错误、成品核对错误、打包运输错误显著低于对照组（P<0.05）为差异显著，有统计学意义。结论 信息闭环化管理降低了肠外营养制剂使用流程中差错的发生率，保障了用药安全性及有效性。
Objective To analyze the role of information closed-loop management in promoting the safe use of neonatal parenteral nutrition preparations. Methods A retrospective analysis was conducted on 2883 prescriptions of parenteral nutrition solution in the Pharmacy Department of Yiwu Maternal and Child Health Hospital from January 2023 to October 2023, which were set as the control group before the implementation of information closed-loop management; From January 2024 to October 2024, the prescription status of 3402 parenteral nutrition solutions in the intravenous drug dispensing center was set as the observation group after the implementation of information closed-loop management. Compare the usage of parenteral nutrition preparations before and after the implementation of the information closed-loop management mode. Results (1) The error rate of the observation group was significantly lower than that of the control group (P<0.05), indicating a statistically significant difference. (2) There are errors in the issuance of medical orders, prescription review, medication dispensing, drug preparation, product verification, packaging and transportation, and discrepancies between wristbands and drug information in the process of using neonatal parenteral nutrition preparations. The observation group had significantly lower errors in prescription issuance, prescription review, medication dispensing, drug preparation, finished product verification, and packaging and transportation compared to the control group (P<0.05), indicating a statistically significant difference. Conclusion Information closed-loop management reduces the incidence of errors in the use process of parenteral nutrition preparations, ensuring medication safety and effectiveness.
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