Analysis of anesthetic efficacy and impact on recovery time of Remimazolam besylate versus propofol in hysteroscopic surgery
苯磺酸瑞马唑仑与丙泊酚用于宫腔镜手术麻醉效果及对苏醒时间影响分析

摘要

目的 分析苯磺酸瑞马唑仑与丙泊酚用于宫腔镜手术麻醉效果及对苏醒时间影响。方法 在2021年1月15日至2024年1月15日期间，本院共收集了90例接受宫腔镜手术的患者作为研究对象。现结合患者就诊顺序，分为新式组45例、传统组45例。新式组45例。传统组采用丙泊酚进行麻醉，新式组应用苯磺酸瑞马唑仑进行麻醉，分析结果。结果 手术前，两组受试者的DBP、SBP、HR以及SPO₂无明显差别，P＞0.05；术中、术后新式组以上指标和术前相比无明显改变，P＞0.05；传统组以上指标和术前相比波动较大，P＜0.05；和常规组相比，观察组的苏醒时间、定向力恢复时间、麻醉起效时间明显更短，P＜0.05；和常规组相比，观察组术后VAS分数更低，P＜0.05；传统组手术不良反应发生率为37.78 %，新式组为4.44 %。和常规组相比，新式组患者手术不良反应发生率更低，P＜0.05。结论 对于接受宫腔镜手术的患者，应用苯磺酸瑞马唑仑完成麻醉效果好于丙泊酚。该法值得进一步推广、应用。

Abstract

Objective To analyze the anesthetic efficacy and impact on recovery time of remimazolam besylate and propofol in hysteroscopic surgery.
Methods A total of 90 patients who underwent hysteroscopic surgery in our hospital from January 15, 2021 to January 15, 2024 were enrolled as research subjects. They were divided into the new group (45 cases) and the traditional group (45 cases) according to the order of medical consultation. The traditional group was anesthetized with propofol, while the new group was anesthetized with remimazolam besylate. The results were analyzed.
Results Before surgery, there were no significant differences in DBP, SBP, HR and SPO₂ between the two groups (P > 0.05). During and after surgery, the above indicators in the new group showed no significant changes compared with those before surgery (P > 0.05), while those in the traditional group fluctuated significantly (P < 0.05). Compared with the traditional group, the new group had significantly shorter recovery time, orientation recovery time and anesthesia onset time (P < 0.05). The postoperative VAS score in the new group was lower than that in the traditional group (P < 0.05). The incidence of adverse reactions was 37.78% in the traditional group and 4.44% in the new group. The new group had a significantly lower incidence of surgical adverse reactions than the traditional group (P < 0.05).
Conclusion   For patients undergoing hysteroscopic surgery, remimazolam besylate has better anesthetic efficacy than propofol. This method is worthy of further promotion and application.