Clinical efficacy study of modified Chaihu Shugan decoction in the treatment of hypertension with anxiety
柴胡疏肝汤加减治疗高血压病伴焦虑的临床疗效研究

摘要

目的 本研究通过随机对照试验评估柴胡疏肝汤加减方案对高血压伴焦虑患者的综合干预效果。方法 共纳入我院162例符合标准受试者，使用随机数字表法分为观察组（中西医联合）与对照组（常规降压）。结果 治疗组24小时平均收缩压下降、HAMA量表评分改善及中医证候积分变化均显著优于对照组（P<0.05）。结论 降压基础上联合中医疏肝解郁法可能对改善高血压合并焦虑患者的自主神经功能紊乱，西药提供即时的血流动力学稳定，中药则通过多组分系统调节恢复机体自愈潜能。

Abstract

Objective To evaluate the comprehensive intervention effect of Chaihu Shugan decoction on patients with hypertension and anxiety through randomized controlled trial.
Methods A total of 162 eligible subjects in our hospital were enrolled and randomly divided into an observation group (integrated traditional Chinese and western medicine) and a control group (conventional antihypertensive).
Results Compared with the control group, the treatment group had a significant reduction in 24-hour average systolic blood pressure, an improvement in HAMA scale score, and a significant change in TCM syndrome score (P<0.05).
Conclusion   On the basis of standardized antihypertensive therapy, traditional Chinese medicine therapy for soothing the liver and relieving depression may improve autonomic nervous system dysfunction in patients with hypertension and anxiety. Western medicine can provide immediate hemodynamic stability, while traditional Chinese medicine can restore the body's self-healing potential through multi-component system regulation.