Correlation analysis between carotid artery plaques and acute ischemic stroke in patients with hypertension
比较高血压患者颈动脉斑块与急性缺血性脑卒中之间的相关性

摘要

目的 分析高血压患者病情、颈动脉斑块与急性缺血性脑卒中发病相关性。方法 纳入2019年1月~2024年12月期间接诊原发性高血压患者150例为研究对象，开展临床研究，以患者有无既往急性缺血性脑卒中（AIS）病史分组为单纯高血压组（75例）、高血压合并AIS组（75例）。经收集各组患者临床信息、诊疗资料、颈动脉超声检查结果等信息后，行数据对比研究。比较单纯高血压组、高血压合并AIS组临床资料组间差异；基于单因素分析结果，分析各类因素与高血压患者急性缺血性脑卒中合并风险相关性、预测价值。结果 性别、高血压病程（≥6年）、高血压分级（≥2级），伴吸烟史、饮酒史，低回声斑块、颈动脉斑块数量（≥3个）及颈动脉狭窄程度（≥中度）为高血压患者合并急性缺血性脑卒中单影响因素类型，差异有统计学意义（P＜0.05）；经Logistics回归性分析可知，性别（男性）、高血压病程（≥6年）、高血压分级（≥2级），伴吸烟史、饮酒史，低回声斑块、颈动脉斑块数量（≥3个）及颈动脉狭窄程度（≥中度）均与高血压患者并发急性缺血性脑卒中风险呈正相关性（P＜0.05）。结论 高血压患者年龄、病程、病情进展程度，吸烟、饮酒不良行为，合并高脂血症及颈动脉内斑块性质、多个斑块及斑块形成后颈动脉狭窄程度均可导致其AIS并发风险升高，应针对上述因素加强高血压患者临床预后综合管理，特别是男性患者，以合理规避AIS风险。

Abstract

Objective To explore the effect of traditional Chinese medicine bone-setting combined with guiding exercises in the treatment of adolescent scoliosis.
Methods A total of 100 adolescent patients with scoliosis admitted to our hospital from January 2023 to December 2024 were selected as the research subjects. Fifty patients who received conventional treatment in 2023 were included in the reference group, and another 50 patients who were treated with traditional Chinese medicine bone setting combined with guiding exercises in 2024 were included in the study group. The therapeutic effects were observed. Record the data of the patients' Cobb Angle, parietal vertebral rotation degree, spinal function and quality of life, compare the data differences between groups, and thereby determine the research purpose.
Results By observing the research data of the two groups, the indicators of Cobb Angle and parietal vertebral rotation degree in the study group after treatment were lower than those in the reference group, which was statistically significant (P < 0.05). The comparison of ODI scores showed that the indicators of the study group were lower than those of the reference group, which was statistically significant (P < 0.05). The comparison of the quality of life scores of patients showed that the study group was higher than the reference group, and the difference was statistically significant (P < 0.05).
Conclusion   The treatment of adolescent scoliosis with traditional Chinese medicine bone-setting combined with guiding exercises can effectively improve the spinal deformity of patients, enhance their quality of life, and has wide application value.