International Journal of Clinical Research
International Journal of Clinical Research. 2025; 9: (8) ; 10.12208/j.ijcr.20250387 .
总浏览量: 42
江苏省中医院 江苏南京
*通讯作者: 季春艳,单位:江苏省中医院 江苏南京;
目的 通过观察中药漱口剂结合“治未病”补脾益肾理论穴位贴敷及体质辨食分餐干预幽门螺旋杆菌感染患者家庭成员(配偶)幽门杆菌阳性率指标治疗两种干预方法,观察中医居家特色护理疗法对幽门螺旋杆菌感染患者配偶生活质量的影响。方法 将在江苏省中医院普内科就诊的90例符合入选标准的幽门螺旋杆菌感染阳性患者的配偶,配偶幽门螺旋杆菌感染检测为阴性。随机分为三组:对照组30例,中药煎剂漱口组和中药煎剂漱口结合穴位敷贴组各30例。观察干预3个月后尿素C13幽门螺旋杆菌检测指标、健康调查简表(SF-36)评分、总体疗效评分变化。结果 试验组1、试验组2与对照组DOB值进行比较显示干预前与干预后3个月,有统计学差异,即DOB值低于干预前。三组内干预前后比较SF-36数值,差值均有统计学差异(P<0.05)。试验组2的治疗有效和显效率均高于试验组1、对照组,且差异具有统计学意义(P<0.05)。结论 中药漱口剂结合“治未病”补脾益肾理论穴位贴敷及体质辨食分餐干预幽门螺旋杆菌感染患者家庭成员(配偶)幽门杆菌阳性率指标下降,患者配偶生活质量明显改善,发挥了中医“治未病”的思想和途径,为今后的居家中医特色护理指导有着重要临床意义和社会效益。
Objective To evaluate the impact of two intervention methods on the quality of life of spouses of patients with Helicobacter pylori infection, using traditional Chinese medicine mouthwash combined with acupoint patch therapy and dietary intervention based on the 'prevention before treatment' theory for tonifying the spleen and kidneys. Methods A total of 90 spouses of patients with Helicobacter pylori infection who were tested negative for Helicobacter pylori infection and met the inclusion criteria at the Department of General Internal Medicine, Jiangsu Provincial Hospital of Traditional Chinese Medicine, were randomly divided into three groups: a control group of 30 cases, a group receiving traditional Chinese medicine decoction mouthwash, and a group receiving traditional Chinese medicine decoction mouthwash combined with acupoint patch therapy, each consisting of 30 cases. The changes in urea C13 Helicobacter pylori detection indicators, Health Survey Questionnaire (SF-36) scores, and overall efficacy scores were observed after 3 months of intervention. Results Compared with the control group, the DOB values of the experimental group 1 and the experimental group 2 showed statistically significant differences before and 3 months after the intervention, indicating that the DOB values were lower than before the intervention. The SF-36 scores within the three groups showed statistically significant differences before and after the intervention (P<0.05). The treatment effectiveness and significant efficiency of the experimental group 2 were higher than those of the experimental group 1 and the control group, with statistically significant differences (P<0.05). Conclusion The combination of traditional Chinese medicine mouthwash with the 'prevention before illness' theory, which involves acupoint patch application and dietary intervention based on individual constitution, has reduced the positive rate of Helicobacter pylori infection among family members (spouses) of patients. This approach has significantly improved the quality of life for the patients 'spouses, embodying the concept and method of' prevention before illness' in traditional Chinese medicine. It holds significant clinical importance and social benefits for guiding future home-based TCM characteristic nursing care.
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