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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2025; 9: (6) ; 10.12208/j.ijcr.20250311 .

Analysis of the therapeutic effect and safety of hyperbaric oxygen therapy on cognitive dysfunction in patients with hypertensive intracerebral hemorrhage
高压氧对高血压脑出血患者认知功能障碍的治疗效果及安全性分析

作者： 杨通, 冯志梅, 陆艳梅 *

合浦县人民医院 广西北海

*通讯作者： 陆艳梅,单位：合浦县人民医院 广西北海；

引用本文: 杨通, 冯志梅, 陆艳梅 高压氧对高血压脑出血患者认知功能障碍的治疗效果及安全性分析[J]. 国际临床研究杂志, 2025; 9: (6) : 158-160.
Published: 2025/6/27 13:15:55

摘要

目的 观察对高血压脑出血患者认知功能障碍患者开展高压氧治疗的效果。方法 本研究通过随机对照试验探讨高压氧（Hyperbaric Oxygen,HBO）治疗时机对高血压脑出血（Hypertensive Intracerebral Hemorrhage,HICH）患者认知功能及日常生活能力的影响。纳入90例HICH患者，分为对照组（30例）、A组（术后<1周HBO治疗，30例）和B组（术后>1周HBO治疗，30例）。两组患者持续进行3月治疗，观察患者整体治疗效果、认知功能以及日常生活能力变化情况。结果 结合统计，治疗1个月后：A组总有效率为83.3%，B组为73.3%，对照组为56.7%。治疗3个月后：A组总有效率为86.7%，B组为73.3%，对照组为60.0%，P<0.05。认知功能水平，治疗后A组患者认知功能高于B组，B组患者高于对照组，P<0.05。日常生活能力变化，治疗后A组患者认知功能高于B组，B组患者高于对照组，P<0.05。结论 对高血压脑出血患者认知功能障碍患者开展高压氧治疗，可以提升临床对该部分患者整体治疗有效率，改善患者认知功能，并提升患者日常生活能力。

关键词： 高血压脑出血；高压氧治疗；认知功能障碍；随机对照试验；神经功能评分

Abstract

Objective To observe the effect of hyperbaric oxygen therapy on cognitive impairment patients with hypertensive intracerebral hemorrhage.
Methods This study investigated the effects of timing of hyperbaric oxygen (HBO) treatment on cognitive function and daily living ability in patients with hypertensive intracerebral hemorrhage (HICH) through a randomized controlled trial. 90 patients with HICH were included and divided into a control group (30 cases), group A (30 cases treated with HBO<1 week after surgery), and group B (30 cases treated with HBO>1 week after surgery). Two groups of patients were treated continuously for 3 months, and the overall treatment effect, cognitive function, and changes in daily living abilities were observed.
Results Combined with statistics, after one month of treatment, the total effective rate of Group A was 83.3%, Group B was 73.3%, and the control group was 56.7%. After 3 months of treatment, the total effective rate of Group A was 86.7%, Group B was 73.3%, and the control group was 60.0%, P<0.05. There was no significant difference in cognitive function levels among the three groups before treatment. After treatment, patients in group A had higher cognitive function than those in group B, and patients in group B had higher cognitive function than the control group, P<0.05. Changes in daily living abilities showed no significant difference among the three groups before treatment. After treatment, patients in group A had higher cognitive function than those in group B, and patients in group B had higher cognitive function than the control group, P<0.05.
Conclusion   Hyperbaric oxygen therapy can improve the overall treatment efficiency, cognitive function, and daily living ability of patients with cognitive impairment in hypertensive intracerebral hemorrhage.

Key words： Hypertensive intracerebral hemorrhage; Hyperbaric oxygen therapy; Cognitive impairment; Randomized controlled trials; Neurological function score

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