Efficacy of daggligin combined with insulin in the treatment of elderly diabetes nephropathy and analysis of BUN, 24h UAE, ACR levels
达格列净联合胰岛素治疗老年糖尿病肾病的疗效及BUN,24 h UAE,ACR水平分析

摘要

目的 探讨达格列净联合胰岛素治疗老年糖尿病肾病的临床疗效及对血尿素氮（BUN）、24小时尿蛋白定量（24h UAE）、尿白蛋白肌酐比值（ACR）水平的影响。方法 选取2023年3月至2024 年7月我院收治的68例老年糖尿病患者，随机将患者分为对照组（34 例，单纯胰岛素治疗）与观察组（34 例，达格列净 + 胰岛素治疗）。比较两组血糖指标、肾功能指标及尿蛋白指标。结果 观察组血糖指标、肾指标及尿蛋白指标改善情况都优于对照组（P<0.05）。结论 达格列净联合胰岛素治疗老年糖尿病肾病患者的效果显著，能有效控制血糖，改善肾指标及尿蛋白指标，值得在临床上进行推广及应用。

Abstract

Objective To investigate the clinical efficacy of daggligin combined with insulin in the treatment of elderly diabetes nephropathy and its influence on the levels of blood urea nitrogen (BUN), 24-hour urinary protein quantification (24h UAE), and urinary albumin creatinine ratio (ACR).
Methods 68 elderly patients with diabetes admitted to our hospital from March 2023 to July 2024 were randomly divided into the control group (34 cases, treated with insulin alone) and the observation group (34 cases, treated with dagelin+insulin). Compare two groups of blood glucose indicators, renal function indicators, and urinary protein indicators.
Results The improvement of blood glucose, renal, and urinary protein indicators in the observation group was better than that in the control group (P<0.05).
Conclusion   Daggligin combined with insulin has a significant effect in the treatment of elderly patients with diabetes nephropathy. It can effectively control blood sugar, improve renal indicators and urinary protein indicators, and is worthy of clinical promotion and application.