Study on the correlation between unexplained premature birth and intrauterine infection in premature infants
不明原因早产与早产儿宫内感染相关性的研究

摘要

目的 分析在提高早产儿存活率中探究不明原因早产与早产儿宫内感染相关性。方法 回顾性收集分析大庆市人民医院2021年1月-2022年12月期间我科收治的早产儿 120例，将不明原因早产出生的早产儿80例作为观察组，将非感染性因素早产的40例作为对照组，对比白细胞介素、C反应蛋白、降钙素原、中性粒细胞百分比。结果 观察组炎性物质水平等均高于对照组，提示观察组胎儿羊水内感染，对比有统计学意义（P﹤0.05）。结论 不明原因早产与早产儿宫内感染相关性成正相关，检查可见炎性标志物水平提高，临床应当注重分析产妇围产因素，预防和警惕早产儿宫内感染，提高其存活率。

Abstract

Objective To explore the correlation between unexplained preterm birth and intrauterine infection in preterm infants in order to improve the survival rate of preterm infants.
Methods A retrospective analysis was conducted on 120 preterm infants admitted to our department of the Daqing People's Hospital from January 2021 to December 2022. Among them, 80 preterm infants born due to unexplained preterm birth were assigned to the observation group, and 40 preterm infants born due to non-infectious factors were assigned to the control group. The levels of interleukin, C-reactive protein, procalcitonin, and the percentage of neutrophils were compared.
Results The levels of inflammatory substances in the observation group were significantly higher than those in the control group, suggesting intrauterine infection in the amniotic fluid of the observation group. The comparison was statistically significant (P < 0.05).
Conclusion   Unexplained preterm birth is positively correlated with intrauterine infection in preterm infants. Elevated levels of inflammatory markers can be observed. Clinically, attention should be paid to analyzing the perinatal factors of the mother to prevent and be vigilant against intrauterine infection in preterm infants and improve their survival rate.