International Journal of Clinical Research
International Journal of Clinical Research. 2025; 9: (6) ; 10.12208/j.ijcr.20250282 .
总浏览量: 64
1 大理大学临床医学院 云南大理
2 大理大学第二附属医院 云南昆明
*通讯作者： 李海峰,单位： 大理大学第二附属医院 云南昆明；
静脉血栓栓塞症（VTE）包括深静脉血栓形成（DVT）和肺栓塞（PE），是一种高发病率、高致死率的血栓性疾病。其发病机制涉及血液成分异常、血管内皮损伤、炎症-免疫激活及遗传易感性等，多种因素交互作用导致凝血-纤溶失衡。目前预防策略基于风险评估，以机械和药物预防为核心。未来研究将聚焦于构建多维度风险预测模型与精准分层干预，以降低VTE的疾病负担。
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a highly prevalent and lethal thrombotic disease. Its pathogenesis involves abnormalities in blood components, endothelial damage, inflammatory-immune activation, and genetic susceptibility, with multiple factors interacting to lead to coagulation-fibrinolytic imbalance. Current prevention strategies are based on risk assessment, with mechanical and pharmacological interventions at the core. Future research will focus on developing multidimensional risk prediction models and precise stratified interventions to reduce the burden of VTE.
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