Research on the treatment of vulvar leukoplakia of liver kidney yin deficiency type with Zilian Gao combined with testosterone propionate based on the holistic concept of traditional Chinese medicine
基于中医整体观念下紫连膏联合丙酸睾酮治疗肝肾阴虚型外阴白斑的研究

摘要

目的 本文旨在探讨紫连膏联合丙酸睾酮治疗肝肾阴虚型外阴白斑的临床疗效。方法 在2023年3月－2024年3月收治的肝肾阴虚型外阴白斑患者中选取100例作为研究对象，随机分为对照组（50例，丙酸睾酮治疗）与观察组（50例，紫连膏联合丙酸睾酮治疗）。对比两组治疗前后症状评分（瘙痒、皲裂、色素减退）以及生活质量。结果 观察组症状评分均低于对照组，生活质量均高于对照组，有统计学意义（P<0.05）。结论 紫连膏联合丙酸睾酮可协同增效，显著改善肝肾阴虚型外阴白斑患者的临床症状，提高患者生活质量，促进康复。

Abstract

Objective This article aims to explore the clinical efficacy of Zilian Gao combined with testosterone propionate in the treatment of vulvar leukoplakia of liver kidney yin deficiency type.
Methods 100 patients with vulvar leukoplakia of liver kidney yin deficiency type admitted from March 2023 to March 2024 were selected as the study subjects and randomly divided into a control group (50 cases, treated with testosterone propionate) and an observation group (50 cases, treated with Zilian Gao combined with testosterone propionate). Compare the symptom scores (itching, cracking, hypopigmentation) and quality of life between two groups before and after treatment.
Results The symptom scores of the observation group were lower than those of the control group, and the quality of life was higher than that of the control group, with statistical significance (P<0.05).
Conclusion   The combination of Zilian Gao and testosterone propionate can synergistically enhance the efficacy, significantly improve the clinical symptoms of patients with vulvar leukoplakia of liver kidney yin deficiency type, enhance their quality of life, and promote rehabilitation.