International Journal of Clinical Research
International Journal of Clinical Research. 2025; 9: (6) ; 10.12208/j.ijcr.20250275 .
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惠州市中心人民医院生殖医学中心 广东惠州
*通讯作者： 王春燕,单位：惠州市中心人民医院生殖医学中心 广东惠州；
首先要探求信息-知识-信仰-行为模型(IKAP模型)对PCOS患者的干预作用，于2022年9月~2023年8月期间选择我们本机构在册的PCOS患者共624例，并将患者分入两个组，组1组2分别接受相应的门诊诱导排卵疗法、宫腔内人工授精技术、辅助生殖技术试管婴儿。其中，组1在治疗的过程中采取了IKAP方案进行干预，而组2没有采取相关措施。将两组的促性腺激素(Gonadotrophin-releasinghormone,Gn)的剂量以及时间等相比较。研究结果显示，试验组相比其控制组，应用促性腺激素剂量更低并且Gn疗程更少(p<0.05)。同时，试验组通过门诊诱导排卵技术、宫腔内人工授精技术以及IVF获得的生物性成功率、临床怀孕成功率均高于其控制组并且试验组利用IVF获得卵子数目比其控制组还要多。我们由此可知，采用IKAP方案对PCOS进行干预能够降低患者的医疗成本，提高PCOS的生物妊娠和临床妊娠成功率。
Firstly, the intervention effect of the information-knowledment-faith-behavior model (IKAP model) on PCOS patients was explored. A total of 624 patients with PCOS registered in our institution were selected from September 2022 to August 2023, and the patients were divided into two groups. Group 1 and group 2 received the corresponding outpatient induced ovulation therapy, intrauterine artificial insemination technology and assisted reproductive technology in vitro. Among them, group 1 took IKAP regimen during the course of treatment, while group 2 did not take relevant measures. The dose and timing of Gonadotrophin-releasinghormone (Gn) were compared between the two groups. The results showed that the trial group received lower gonadotropin dose and fewer Gn courses than the control group (p<0.05). At the same time, the biological success rate and clinical pregnancy success rate of the experimental group through outpatient induced ovulation technology, intrauterine insemination technology and IVF were higher than those of the control group, and the number of eggs obtained by IVF in the experimental group was higher than that of the control group. We can conclude that the intervention of PCOS with IKAP protocol can reduce the medical cost of patients and improve the biological and clinical pregnancy success rate of PCOS.
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