International Journal of Clinical Research
International Journal of Clinical Research. 2025; 9: (5) ; 10.12208/j.ijcr.20250234 .
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1 河北大学护理学院 河北保定
2 河北大学附属医院 河北保定
*通讯作者: 石磊,单位: 河北大学护理学院 河北保定;
糖尿病现已经成为世界各地突出的公共卫生问题,发病风险较高,可引发多种并发症。刺梨是我国西南地区广泛种植的重要植物资源,也是我国传统的食药用植物,因其营养价值高、保健功能强而深受消费者青睐。多糖、多酚、三萜类等成分是刺梨中的主要天然活性成分,具有多种生理活性和药用价值,并表现出显著的抗糖尿病作用。本文综述了刺梨中主要活性成分在降低血糖,以及调节血脂、抗氧化、改善炎症状态等糖尿病并发症中的有效作用,探讨了这些活性成分在糖尿病发病机制中的代谢机理,进一步阐明了刺梨调节血糖的作用机制。
Diabetes has become a prominent public health problem around the world, with a high risk of onset and multiple complications. Rosa roxburghii is an important plant resource widely planted in southwest China, and is also a traditional edible and medicinal plant in China. Highly favored by consumers due to its nutritional value and powerful health benefits, as well as its high cost-effectiveness. Polysaccharides, polyphenols and triterpenoids are the main natural active components in Rosa roxburghii, which have many physiological activities and medicinal values, and show significant anti-diabetic effects. This paper reviewed the effective effects of the main active components in Rosa roxburghii on lowering blood glucose, regulating blood lipid, antioxidation and improving inflammatory state of diabetes mellitus, discussed the metabolic mechanism of these active components in the pathogenesis of diabetes mellitus, and further clarifies the mechanism of Rosa roxburghii regulating blood glucose.
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