Application of PDCA cycle in safe infusion management of enzyme replacement therapy in Pompe disease
PDCA循环法在儿童庞贝病酶替代治疗药物安全输注管理中的运用研究

摘要

目的 分析PDCA循环法在儿童庞贝病酶替代治疗药物安全输注管理中的效果。方法 本次研究的起始时间为2021年11月份，截止时间为2024年6月份，患儿的数量10例，分成对照组和实验组，对照组常规护理，实验组PDCA循环管理，分析两组患儿不良事件发生率，评估患儿家属的心理状态。结果 两组患儿通过提供不同的护理措施后，实验组患儿不良事件发生率更低，p<0.05，分析患儿家属的心理状态，实验组患儿家属的心理状态更为稳定，p<0.05。结论 为儿童庞贝病酶替代治疗药物安全输液管理中开展PDCA循环管理模式，可以提升患儿的护理效果，降低患儿出现不良反应的风险，改善患儿家属的心理状态，值得提倡。

Abstract

Objective To analyze the effect of PDCA cycle in the safe infusion management of enzyme replacement therapy for children with Pompeii disease.
Methods The study started in November 2021 and ended in December 2023. 26 cases of children were divided into control group and experimental group, routine nursing in the control group, PDCA cycle management in the experimental group, the incidence of adverse events in the two groups of children were analyzed, and the psychological state of their families was assessed.
Results After the two groups of children were provided with different nursing measures, the incidence of adverse events in the experimental group was lower, p<0.05. The psychological state of the families of the children was analyzed, and the psychological state of the families of the children in the experimental group was more stable, p<0.05.
Conclusion   The implementation of PDCA cycle management mode in the safe infusion management of enzyme replacement therapy for children with Pompeii disease can improve the nursing effect of children, reduce the risk of adverse reactions in children, and improve the psychological state of children's families, which is worth advocating.