The effect of vitamin K3 injection in the treatment of pediatric bronchiolitis
维生素K3注射液治疗小儿毛细支气管炎的效果

摘要

目的 探析小儿毛细支气管炎应用维生素K3注射液治疗的价值。方法 抽选本院收治共96例小儿毛细支气管炎患儿并随机划分2组（时段2024年1月-2024年12月），对照组（n=48）予以布地奈德雾化治疗，观察组（n=48）在此基础上联合维生素K3注射液治疗。根据疗效评估、病症缓解时间、炎性指标评价2组治疗效果。结果 观察组治疗总有效率相比对照组提高（P＜0.05）。观察组发热、咳嗽、呼吸困难、肺啰音消退时间相比对照组缩短（P＜0.05）。观察组治疗7d后白细胞介素-6（IL-6）、C反应蛋白（CRP）、肿瘤坏死因子-α（TNF-α）相比对照组下降（P＜0.05）。结论 小儿毛细支气管炎应用维生素K3注射液治疗可提升疗效，加快病症缓解，减轻炎症反应。

Abstract

Objective To explore the value of using vitamin K3 injection for the treatment of pediatric bronchiolitis.
Methods A total of 96 children with bronchiolitis admitted to our hospital were randomly divided into two groups (January 2024 December 2024). The control group (n=48) received budesonide nebulization treatment, while the observation group (n=48) received combined treatment with vitamin K3 injection on this basis. Evaluate the therapeutic effect of two groups based on efficacy evaluation, disease relief time, and inflammatory indicators. The total effective rate of the observation group was higher than that of the control group (P<0.05). The observation group had a shorter time for fever, cough, dyspnea, and disappearance of lung rales compared to the control group (P<0.05). After 7 days of treatment, the levels of interleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor alpha (TNF - α) in the observation group decreased compared to the control group (P<0.05).
Conclusion   The application of vitamin K3 injection in the treatment of pediatric bronchiolitis can improve efficacy, accelerate disease relief, and alleviate inflammatory reactions.