Application of drug coated balloon in coronary intervention therapy
冠脉介入治疗中药物涂层球囊的应用

摘要

目的 探讨经皮冠状动脉介入（PCI）治疗中药物涂层球囊（DCB）的应用意义。方法 回顾性分析2021年1月至2025年1月期间在本院行PCI治疗的100例患者资料，根据患者选择的治疗方式不同分为常规介入组（n=50）和DCB组（n=50），收集两组治疗数据，分析不同治疗策略的效果。结果 两组患者术前、术后即刻最小管腔直径对比无明显差异（P＞0.05），术后6个月，常规介入组最小管腔直径明显更小（P＜0.05）；术前，两组患者心功能指标对比无明显差异（P＞0.05），术后，常规介入组LVEDd、LVESd值更高，而LVEF值更低（P＜0.05）；与常规介入组相比，DCB组不良事件发生率明显更低（P＜0.05）。结论 PCI治疗过程中应用DCB可获得满意效果，有助于改善患者心功能，且安全性高，具有临床应用与推广价值。

Abstract

Objective To explore the application significance of drug coated balloon (DCB) in percutaneous coronary intervention (PCI) treatment.
Methods A retrospective analysis was conducted on 100 patients who underwent PCI treatment in our hospital from January 2021 to January 2025. The patients were divided into a conventional intervention group (n=50) and a DCB group (n=50) based on their chosen treatment method. Treatment data from both groups were collected to analyze the effectiveness of different treatment strategies.
Results There was no significant difference in the minimum lumen diameter between the two groups of patients before and immediately after surgery (P>0.05). At 6 months after surgery, the minimum lumen diameter in the conventional intervention group was significantly smaller (P<0.05); Before surgery, there was no significant difference in cardiac function indicators between the two groups of patients (P>0.05). After surgery, the LVEDd and LVESd values were higher in the conventional intervention group, while the LVEF value was lower (P<0.05); Compared with the conventional intervention group, the incidence of adverse events in the DCB group was significantly lower (P<0.05).
Conclusion   The application of DCB during PCI treatment can achieve satisfactory results, help improve patients' cardiac function, and has high safety, with clinical application and promotion value.