Effect of Yangxue oral liquid on blood gas indexes in patients with chronic bronchitis
养血口服液对慢性支气管炎患者血气指标的影响

摘要

目的 探讨养血口服液与西医常规治疗治疗下对慢性支气管炎患者的血气指标的影响。方法 本次研究时间起始于2021.6，结束于2022.5，纳入对象均为确诊的慢性支气管炎患者，共计200例，将200例患者运用数字表法进行分组，分为对照组（100例）、治疗组（100例）。两组均采用相同的西医常规治疗，对照组予以阿莫西林胶囊、盐酸氨溴索、氨茶碱片治疗；治疗组联合养血口服液治疗。比较两组疗效、血气分析指标[血氧饱和度（SaO2）、动脉血二氧化碳（PaCO2）、动脉氧分压（PaO2）]、临床证候积分（咳嗽、咳痰、肺部哮鸣、呼吸困难、纳呆腹胀、便溏以及乏力肢重证候）、临床证候消退时间、安全性方面的信息。结果 治疗组总有效率（98.00%）优于对照组（89.00%）；治疗后SaO2均高于对照组，PaCO2低于对照组（P<0.05）；治疗组临床证候、体征积分改善明显好于对照组，临床证候消退时间也低于对照组（P<0.05）；安全性方面，对照组不良反应发生率8.00%高于治疗组0.00%，差异明显（P<0.05）。结论 养血口服液治疗盐酸氨溴索治疗慢性支气管炎疗效确切，可以提高机体的免疫力，改善血气分析指标，而且安全可靠。

Abstract

Objective To explore the effect of Yangxue oral liquid and conventional western medicine treatment on blood gas indexes in patients with chronic bronchitis.
Methods The study started in June 2021 and ended in May 2022. The subjects included were all confirmed chronic bronchitis patients, a total of 200 cases, and the 200 patients were divided into control group (100 cases) and treatment group (100 cases) using the digital table method. Both groups received the same conventional western medicine treatment. The control group was treated with amoxicillin capsules, ambroxol hydrochloride, and aminophylline tablets; the treatment group was treated with Yangxue oral liquid. The efficacy, blood gas analysis indicators [blood oxygen saturation (SaO2), arterial carbon dioxide (PaCO2), arterial oxygen partial pressure (PaO2)], clinical symptom scores (cough, sputum, lung wheezing, dyspnea, anorexia, abdominal distension, loose stools, and weakness and heaviness in limbs), clinical symptom resolution time, and safety information were compared between the two groups.
Results The total effective rate (98.00%) of the treatment group was better than that of the control group (89.00%); after treatment, SaO2 was higher than that of the control group, and PaCO2 was lower than that of the control group (P<0.05); the improvement of clinical symptom and sign scores in the treatment group was significantly better than that in the control group, and the time of clinical symptom resolution was also shorter than that in the control group (P<0.05); in terms of safety, the incidence of adverse reactions in the control group was 8.00% higher than that in the treatment group (0.00%), with significant differences (P<0.05).
Conclusion   Yangxue oral liquid has a definite effect on the treatment of chronic bronchitis with ambroxol hydrochloride, can improve the body's immunity, improve blood gas analysis indicators, and is safe and reliable.