Nursing strategies and analysis of peripheral neurotoxicity caused by oxaliplatin in patients with gastrointestinal tumors
消化道肿瘤患者应用奥沙利铂引起周围神经毒性的护理对策及分析

摘要

目的 分析消化道肿瘤患者应用奥沙利铂引起周围神经毒性的护理对策。方法 随机选取2023年1月至2024年1月期间在我院接受奥沙利铂化疗的消化道肿瘤患者70例，分组采取随机数字表法，共分成观察组和对照组各有35例。对照组化疗期间给予常规护理，观察组开展预见性护理，将两组护理效果进行对比分析。结果 两组结果比较后显示，观察组护理管理质量以及患者的遵医行为与对照组相比明显提升，患者出现的周围神经毒性反应明显少于对照组，最终患者的生存质量同对照组比较明显提升，差异有统计学意义（P<0.05）。结论 对消化道肿瘤患者应用奥沙利铂化疗期间开展预见性护理干预，可进一步提升临床护理质量，增强患者的遵医行为，减轻患者化疗所引起的神经毒性反应，提高患者的生存质量。

Abstract

Objective To analyze the nursing countermeasures of peripheral nerve toxicity caused by oxaliplatin in patients with digestive tract tumors.
Methods 70 gastrointestinal tumor patients receiving oxaliplatin chemotherapy in our hospital from January 2023 to January 2024 were randomly selected, and 35 patients were divided into observation group and control group respectively. The control group gave routine nursing during chemotherapy, the observation group carried out predictive nursing, and the nursing effect of the two groups was compared.
Results The comparison of the two groups showed that the quality of nursing management and the compliance behavior of the patients in the observation group were significantly improved compared with that of the control group, the peripheral nerve toxic response of the patients was significantly less than that of the control group, and the quality of life of the final patients was significantly improved compared with that of the control group, and the difference was statistically significant (P <0.05).
Conclusion   The tive nursing intervention during oxaliplatin chemotherapy for patients with digestive tract tumors can further improve the quality of clinical care, enhance the compliance behavior of patients, reduce the neurotoxic reaction caused by chemotherapy, and improve the survival quality of patients.