Application of different doses of methylprednisolone in children with mycoplasma pneumonia
不同剂量甲泼尼龙在小儿支原体肺炎中的应用

摘要

目的 分析在小儿支原体肺炎中的临床治疗方案中应用不同剂量甲泼尼龙的医学效果。方法 将2023年12月-2024年11月内于我院儿科门诊就诊的小儿支原体肺炎患者104例分52例对照组常规治疗增加低剂量甲泼尼龙治疗，而52例观察组则为高剂量甲泼尼龙治疗。对比两组临床症状改善时间、不良反应。结果 观察组临床症状改善时间优于对照组，指标对比有统计学意义（P﹤0.05）。不良反应对比差异不具有统计学意义，（P﹥0.05）。结论 在小儿支原体肺炎中的治疗中应用高剂量甲泼尼龙可尽快缓解临床症状，促患儿躯体舒适，且高剂量用药并不会增加不良反应，用药安全性较高。

Abstract

Objective To analyze the medical effects of different doses of methylprednisolone in the clinical treatment of Mycoplasma pneumoniae pneumonia in children.
Methods A total of 104 pediatric patients with mycoplasma pneumonia who visited our pediatric outpatient department from December 2023 to November 2024 were divided into a control group of 52 patients who received conventional treatment plus low-dose methylprednisolone treatment, while the observation group of 52 patients received high-dose methylprednisolone treatment. Compare the improvement time of clinical symptoms and adverse reactions between two groups.
Results The improvement time of clinical symptoms in the observation group was better than that in the control group, and the comparison of indicators was statistically significant (P<0.05). The difference in adverse reactions was not statistically significant (P>0.05).
Conclusion   The use of high-dose methylprednisolone in the treatment of Mycoplasma pneumoniae pneumonia in children can quickly alleviate clinical symptoms, promote physical comfort in children, and high-dose medication does not increase adverse reactions, with high medication safety.