Analysis of the therapeutic effect of cetirizine hydrochloride combined with calcium gluconate, vitamin C, etc. in the treatment of acute and chronic urticaria
盐酸西替利嗪联合葡萄糖酸钙、维生素C等治疗急慢性荨麻疹的疗效分析

摘要

目的 分析急慢性荨麻疹患者使用盐酸西替利嗪联合葡萄糖酸钙、维生素C等治疗的临床疗效。方法 纳入2022年6月~2023年6月内收治的急慢性荨麻疹患者76例，按照治疗方式分为对照组（补充葡萄糖酸钙和维生素C治疗）和观察组（加用盐酸西替利嗪治疗）各38例，对比两组临床疗效。结果 干预前两组临床症状积分差异无统计学意义，治疗后观察组患者临床症状积分显著低于对照组，差异均有统计学意义（P＜0.05）。且对比两组用药不良反应显示，观察组不良反应显著低于对照组，差异均有统计学意义（P＜0.05）。结论 对急慢性荨麻疹患者行盐酸西替利嗪联合葡萄糖酸钙、维生素C治疗能够显著改善患者临床症状，用药安全性较高。

Abstract

Objective To analyze the clinical efficacy of using cetirizine hydrochloride combined with calcium gluconate, vitamin C, and other treatments in patients with acute and chronic urticaria.
Methods 76 patients with acute and chronic urticaria admitted between June 2022 and June 2023 were included and divided into a control group (supplemented with calcium gluconate and vitamin C) and an observation group (treated with cetirizine hydrochloride), with 38 cases in each group, according to the treatment method. The clinical efficacy of the two groups was compared.
Results There was no statistically significant difference in clinical symptom scores between the two groups before intervention. After treatment, the clinical symptom scores of the observation group were significantly lower than those of the control group, and the differences were statistically significant (P<0.05). And comparing the adverse reactions of the two groups of medication, the adverse reactions in the observation group were significantly lower than those in the control group, and the differences were statistically significant (P<0.05).
Conclusion   The combination therapy of cetirizine hydrochloride, calcium gluconate, and vitamin C can significantly improve the clinical symptoms of patients with acute and chronic urticaria, and the medication safety is relatively high.