The role of cervical HPV detection in screening cervical precancerous lesions
宫颈HPV检测在宫颈癌前病变筛选中的作用

摘要

目的 分析宫颈HPV检测在宫颈癌前病变筛选中的作用。方法 将本院于2023年03月-2024年09月收治的140例宫颈疾病患者作为研究对象，所有患者均在本院进行宫颈HPV检测及阴道镜下宫颈活检。将宫颈活检结果作为金标准，计算HPV检测检测结果及所检出的HPV阳性患者中HPV-NDA亚型检出结果。结果 （1）HPV检测出116例阳性，检出率为96.67%，与宫颈活检结果差异无统计学意义（P＞0.05）。（2）对阳性患者中HPV-NDA亚型检出结果进行分析，HPV16型检出率为54.46%，HPV18型检出率为22.32%，HPV52型检出率为13.39%，其次为HPV31型、HPV35型。结论 HPV感染与宫颈癌前病变密切相关，其中以HPV16、52、18亚型最为常见，因此早期开展宫颈HPV检测在宫颈癌前病变筛选中具有重要作用。

Abstract

Objective To analyze the role of cervical HPV detection in screening cervical precancerous lesions.
Methods 140 patients with cervical diseases admitted to our hospital from September 2023 to September 2024 were selected as research objects. All patients underwent cervical HPV detection and colposcopic cervical biopsy in our hospital. Cervical biopsy results were used as the gold standard to calculate HPV test results and HPV-NDA subtypes in HPV-positive patients detected.
Results (1) HPV was detected in 116 cases, the detection rate was 96.67%, and the difference was not statistically significant compared with the cervical biopsy results (P > 0.05). (2) The detection results of HPV-NDA subtypes in positive patients were analyzed. The detection rate of HPV16 was 54.46%, the detection rate of HPV18 was 22.32%, and the detection rate of HPV52 was 13.39%, followed by HPV31 and HPV35.
Conclusion   HPV infection is closely related to cervical precancerous lesions, among which the most common subtypes are HPV16, 52 and 18. Therefore, early cervical HPV detection plays an important role in screening cervical precancerous lesions.